Opportunities and challenges in the diagnostic utility of dermal interstitial fluid

M Friedel, IAP Thompson, G Kasting, R Polsky… - Nature Biomedical …, 2023 - nature.com
The volume of interstitial fluid (ISF) in the human body is three times that of blood. Yet,
collecting diagnostically useful ISF is more challenging than collecting blood because the …

Microneedle sensors for point‐of‐care diagnostics

Y Hu, E Chatzilakou, Z Pan, G Traverso… - Advanced …, 2024 - Wiley Online Library
Abstract Point‐of‐care (POC) has the capacity to support low‐cost, accurate and real‐time
actionable diagnostic data. Microneedle sensors have received considerable attention as an …

Encoded structural color microneedle patches for multiple screening of wound small molecules

M Lu, X Zhang, D Xu, N Li, Y Zhao - Advanced Materials, 2023 - Wiley Online Library
Detection of biomarkers associated with wound conditions provides in‐depth healthcare
information and benefits wound healing treatment. The current aim of wound detection is to …

Wearable aptalyzer integrates microneedle and electrochemical sensing for in vivo monitoring of glucose and lactate in live animals

F Bakhshandeh, H Zheng, NG Barra… - Advanced …, 2024 - Wiley Online Library
Continuous monitoring of clinically relevant biomarkers within the interstitial fluid (ISF) using
microneedle (MN)‐based assays, has the potential to transform healthcare. This study …

A conductive hydrogel microneedle‐based assay integrating PEDOT: PSS and Ag‐Pt nanoparticles for real‐time, enzyme‐less, and electrochemical sensing of …

P GhavamiNejad, A GhavamiNejad… - Advanced …, 2023 - Wiley Online Library
Continuous glucose meters (CGMs) have tremendously boosted diabetes care by
emancipating millions of diabetic patients' need for repeated self‐testing by pricking their …

Recent developments and future perspectives of microfluidics and smart technologies in wearable devices

S Apoorva, NT Nguyen, SK Rajan - Lab on a Chip, 2024 - pubs.rsc.org
Wearable devices are gaining popularity in the fields of health monitoring, diagnosis, and
drug delivery. Recent advances in wearable technology have enabled real-time analysis of …

Technological Advances of Wearable Device for Continuous Monitoring of In Vivo Glucose

X Huang, C Yao, S Huang, S Zheng, Z Liu, J Liu… - ACS …, 2024 - ACS Publications
Managing diabetes is a chronic challenge today, requiring monitoring and timely insulin
injections to maintain stable blood glucose levels. Traditional clinical testing relies on …

A review of recent advances in microneedle-based sensing within the dermal ISF that could transform medical testing

J Li, M Wei, B Gao - ACS sensors, 2024 - ACS Publications
Interstitial fluid (ISF) has attracted extensive attention in an extremely wide range of areas
due to its unique advantages, such as portability, high precision, comfortable operation, and …

Hydrogel-coated SERS microneedles for drug monitoring in dermal interstitial fluid

Y Li, Y Wang, R Mei, B Lv, X Zhao, L Bi, H Xu… - ACS …, 2024 - ACS Publications
In vivo drug monitoring is crucial for evaluating the effectiveness and safety of drug
treatment. Blood sampling and analysis is the current gold standard but needs professional …

Swellable colorimetric microneedles for glucose detection based on glucose oxidase-like gold nanoparticles

X Li, J Lv, J Zhao, G Ling, P Zhang - Analytica Chimica Acta, 2024 - Elsevier
Background Regular blood glucose monitoring is very important for diabetic patients. The
composition of skin interstitial fluid (ISF) is similar to that of blood, which can be used for …