Biocatalysis making waves in organic chemistry
Biocatalysis has an enormous impact on chemical synthesis. The waves in which
biocatalysis has developed, and in doing so changed our perception of what organic …
biocatalysis has developed, and in doing so changed our perception of what organic …
Enzyme co-immobilization: Always the biocatalyst designers' choice… or not?
The increasing relevance of cascade reactions in biocatalysis has sparked a great interest
for enzyme co-immobilization. Enzyme co-immobilization allows access to some kinetic …
for enzyme co-immobilization. Enzyme co-immobilization allows access to some kinetic …
Artificial biocatalytic linear cascades for preparation of organic molecules
The review compiles artificial cascades involving enzymes with a focus on the last 10 years.
A cascade is defined as the combination of at least two reaction steps in a single reaction …
A cascade is defined as the combination of at least two reaction steps in a single reaction …
The rise of continuous flow biocatalysis–fundamentals, very recent developments and future perspectives
Biocatalysis community has witnessed a drastic increase in the number of studies for the use
of enzymes in continuously operated flow reactors. This significant interest arose from the …
of enzymes in continuously operated flow reactors. This significant interest arose from the …
Round, round we go–strategies for enzymatic cofactor regeneration
S Mordhorst, JN Andexer - Natural product reports, 2020 - pubs.rsc.org
Covering: up to the beginning of 2020 Enzymes depending on cofactors are essential in
many biosynthetic pathways of natural products. They are often involved in key steps …
many biosynthetic pathways of natural products. They are often involved in key steps …
Transaminase biocatalysis: optimization and application
F Guo, P Berglund - Green Chemistry, 2017 - pubs.rsc.org
Transaminases (TAs) are one of the most promising biocatalysts in organic synthesis for the
preparation of chiral amino compounds. The concise reaction, excellent enantioselectivity …
preparation of chiral amino compounds. The concise reaction, excellent enantioselectivity …
Cofactor NAD (P) H regeneration inspired by heterogeneous pathways
X Wang, T Saba, HHP Yiu, RF Howe, JA Anderson… - Chem, 2017 - cell.com
Biocatalysis can empower chemical, pharmaceutical, and energy industries, where the use
of enzymes facilitates low-energy, sustainable methods of producing high-value chemicals …
of enzymes facilitates low-energy, sustainable methods of producing high-value chemicals …
Enzyme immobilization in hydrogels: A perfect liaison for efficient and sustainable biocatalysis
Biocatalysis is an established chemical synthesis technology that has by no means been
restricted to research laboratories. The use of enzymes for organic synthesis has evolved …
restricted to research laboratories. The use of enzymes for organic synthesis has evolved …
Biocatalytic imine reduction and reductive amination of ketones
JH Schrittwieser, S Velikogne… - Advanced Synthesis & …, 2015 - Wiley Online Library
Chiral amines represent a prominent functional group in pharmaceuticals and
agrochemicals and are hence attractive targets for asymmetric synthesis. Since the …
agrochemicals and are hence attractive targets for asymmetric synthesis. Since the …
The industrial age of biocatalytic transamination
M Fuchs, JE Farnberger… - European Journal of …, 2015 - Wiley Online Library
During the last decade the use of ω‐transaminases has been identified as a very powerful
method for the preparation of optically pure amines from the corresponding ketones. Their …
method for the preparation of optically pure amines from the corresponding ketones. Their …