[HTML][HTML] Diagnosis and management of primary biliary cholangitis

ZM Younossi, D Bernstein, ML Shiffman… - Official journal of the …, 2019 - journals.lww.com
Primary biliary cholangitis (PBC) is a chronic, cholestatic, autoimmune disease with a
variable progressive course. PBC can cause debilitating symptoms including fatigue and …

The biology of NKT cells

A Bendelac, PB Savage, L Teyton - Annu. Rev. Immunol., 2007 - annualreviews.org
Recognized more than a decade ago, NKT cells differentiate from mainstream thymic
precursors through instructive signals emanating during TCR engagement by CD1d …

The British Society of Gastroenterology/UK-PBC primary biliary cholangitis treatment and management guidelines

GM Hirschfield, JK Dyson, GJM Alexander… - Gut, 2018 - gut.bmj.com
Primary biliary cholangitis (formerly known as primary biliary cirrhosis, PBC) is an
autoimmune liver disease in which a cycle of immune mediated biliary epithelial cell injury …

Primary biliary cirrhosis

MM Kaplan, ME Gershwin - New England Journal of Medicine, 2005 - Mass Medical Soc
Primary biliary cirrhosis, a slowly progressive autoimmune liver disease characterized by
portal inflammation and an immune-mediated destruction of the intrahepatic bile ducts …

Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections

J Mattner, KL DeBord, N Ismail, RD Goff, C Cantu III… - Nature, 2005 - nature.com
CD1d-restricted natural killer T (NKT) cells are innate-like lymphocytes that express a
conserved T-cell receptor and contribute to host defence against various microbial …

The immunobiology and pathophysiology of primary biliary cirrhosis

GM Hirschfield, ME Gershwin - Annual review of pathology …, 2013 - annualreviews.org
Primary biliary cirrhosis (PBC) is an autoimmune disease characterized by clinical
homogeneity among patients, an overwhelming female predominance, production of a …

The pathogenesis of primary biliary cholangitis: a comprehensive review

A Lleo, PSC Leung, GM Hirschfield… - Seminars in Liver …, 2020 - thieme-connect.com
Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease characterized by
autoimmune destruction of small to medium size intrahepatic bile ducts. The etiology of PBC …

Liver immunology

DP Bogdanos, B Gao… - Comprehensive …, 2013 - pmc.ncbi.nlm.nih.gov
The liver is the largest organ in the body and is generally regarded by non-immunologists as
not having lymphoid function. However, such is far from accurate. This review highlights the …

Primary biliary cirrhosis

C Selmi, CL Bowlus, ME Gershwin, RL Coppel - The Lancet, 2011 - thelancet.com
Primary biliary cirrhosis is a chronic liver disease characterised by intrahepatic bile-duct
destruction, cholestasis, and, in some cases, cirrhosis. Evidence supporting the autoimmune …

[PDF][PDF] Long noncoding RNA HULC modulates the phosphorylation of YB‐1 through serving as a scaffold of extracellular signal–regulated kinase and YB‐1 to …

D Li, X Liu, J Zhou, J Hu, D Zhang, J Liu, Y Qiao… - …, 2017 - Wiley Online Library
Dysregulated expression of long noncoding RNAs has been reported in many types of
cancers, indicating that it may play a critical role in tumorigenesis. The long noncoding RNA …