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Solvent-free heterocyclic synthesis
MAP Martins, CP Frizzo, DN Moreira, L Buriol… - Chemical …, 2009 - ACS Publications
Heterocycles form, by far, the largest of the classical divisions of organic chemistry.
Moreover, they are of immense importance not only biologically and industrially but also to …
Moreover, they are of immense importance not only biologically and industrially but also to …
Part I: Nitroalkenes in the synthesis of heterocyclic compounds
The applications of nitroalkenes in the synthesis of three-to five-membered O, N and S-
heterocycles, including natural products are investigated in this review. These heterocyclic …
heterocycles, including natural products are investigated in this review. These heterocyclic …
Direct synthesis of pyrroles by dehydrogenative coupling of β-aminoalcohols with secondary alcohols catalyzed by ruthenium pincer complexes.
The search for new atom-economical and green synthetic methods for the synthesis of
functionalized pyrrole derivatives has attracted much attention owing to their potential …
functionalized pyrrole derivatives has attracted much attention owing to their potential …
Catalytic mechanisms of direct pyrrole synthesis via dehydrogenative coupling mediated by PNP-Ir or PNN-Ru pincer complexes: crucial role of proton-transfer …
S Qu, Y Dang, C Song, M Wen… - Journal of the …, 2014 - ACS Publications
Kempe et al. and Milstein et al. have recently advanced the dehydrogenative coupling
methodology to synthesize pyrroles from secondary alcohols (eg, 3) and β-amino alcohols …
methodology to synthesize pyrroles from secondary alcohols (eg, 3) and β-amino alcohols …
Iron (III)-catalyzed four-component coupling reaction of 1, 3-dicarbonyl compounds, amines, aldehydes, and nitroalkanes: a simple and direct synthesis of …
A simple, convenient, and multicomponent coupling strategy for the synthesis of highly
functionalized pyrroles catalyzed by iron (III) salts has been developed. This strategy …
functionalized pyrroles catalyzed by iron (III) salts has been developed. This strategy …
Metal-free nitrogen-doped mesoporous carbons for the mild and selective synthesis of pyrroles from nitroarenes via cascade reaction
X Yu, M Miao, S Huo, X Tang, L Ni, S Liu… - ACS Applied Materials …, 2024 - ACS Publications
The cascade synthesis of pyrroles from nitroarenes is an attractive alternative strategy.
However, metal catalysts and relatively high temperatures cover the existing reported …
However, metal catalysts and relatively high temperatures cover the existing reported …
Design and synthesis of novel series of pyrrole based chemotypes and their evaluation as selective aldose reductase inhibitors. A case of bioisosterism between a …
K Pegklidou, C Koukoulitsa, I Nicolaou… - Bioorganic & Medicinal …, 2010 - Elsevier
Pyrrolyl-propionic and butyric-acid derivatives 1 and 2 were synthesized in order to study the
effect of the variation of the methylene chain in comparison to the previously reported …
effect of the variation of the methylene chain in comparison to the previously reported …
A Catalyst‐and Solvent‐Free Synthesis of Tetra‐Substituted Pyrroles by Multicomponent Reaction
T Pavithra, DB Rajkumar, K Gnanaoli… - …, 2023 - Wiley Online Library
A facile, catalyst‐and solvent‐free, three‐component reaction was developed for the
synthesis of tetrasubstituted pyrroles at room temperature and under white light. The …
synthesis of tetrasubstituted pyrroles at room temperature and under white light. The …
Modular CeCl3· 7H2O-catalyzed multi-component synthesis of 1, 2, 3, 4-tetrasubstituted pyrroles under microwave irradiation and their further trichloroisocyanuric acid …
CC Silveira, SR Mendes, GM Martins, SC Schloesser… - Tetrahedron, 2013 - Elsevier
A modular, multicomponent synthesis of 1, 2, 3, 4-tetrasubstituted pyrroles promoted by the
inexpensive CeCl 3· 7H 2 O, is reported. The reaction was carried out under microwave …
inexpensive CeCl 3· 7H 2 O, is reported. The reaction was carried out under microwave …
A diverse series of substituted benzenesulfonamides as aldose reductase inhibitors with antioxidant activity: design, synthesis, and in vitro activity
P Alexiou, VJ Demopoulos - Journal of medicinal chemistry, 2010 - ACS Publications
We have previously reported the successful replacement of a carboxylic acid functionality
with that of a difluorophenolic group on the known aldose reductase inhibitors (ARIs) of 2 …
with that of a difluorophenolic group on the known aldose reductase inhibitors (ARIs) of 2 …