Mammalian stress granules and P bodies at a glance
Stress granules (SGs) and processing bodies (PBs) are membraneless ribonucleoprotein-
based cellular compartments that assemble in response to stress. SGs and PBs form …
based cellular compartments that assemble in response to stress. SGs and PBs form …
[HTML][HTML] Molecular mechanisms of stress granule assembly and disassembly
Stress granules (SGs) are membrane-less ribonucleoprotein (RNP)-based cellular
compartments that form in the cytoplasm of a cell upon exposure to various environmental …
compartments that form in the cytoplasm of a cell upon exposure to various environmental …
[HTML][HTML] High-density proximity map** reveals the subcellular organization of mRNA-associated granules and bodies
Summary mRNA processing, transport, translation, and ultimately degradation involve a
series of dedicated protein complexes that often assemble into large membraneless …
series of dedicated protein complexes that often assemble into large membraneless …
Stress granules and processing bodies in translational control
P Ivanov, N Kedersha… - Cold Spring Harbor …, 2019 - cshperspectives.cshlp.org
Stress granules (SGs) and processing bodies (PBs) are non-membrane-enclosed RNA
granules that dynamically sequester translationally inactive messenger ribonucleoprotein …
granules that dynamically sequester translationally inactive messenger ribonucleoprotein …
[HTML][HTML] Who's in and who's out—compositional control of biomolecular condensates
Biomolecular condensates are two-and three-dimensional compartments in eukaryotic cells
that concentrate specific collections of molecules without an encapsulating membrane …
that concentrate specific collections of molecules without an encapsulating membrane …
G3BP–Caprin1–USP10 complexes mediate stress granule condensation and associate with 40S subunits
Mammalian stress granules (SGs) contain stalled translation preinitiation complexes that are
assembled into discrete granules by specific RNA-binding proteins such as G3BP. We now …
assembled into discrete granules by specific RNA-binding proteins such as G3BP. We now …
The small molecule ISRIB reverses the effects of eIF2α phosphorylation on translation and stress granule assembly
Previously, we identified ISRIB as a potent inhibitor of the integrated stress response (ISR)
and showed that ISRIB makes cells resistant to the effects of eIF2α phosphorylation and …
and showed that ISRIB makes cells resistant to the effects of eIF2α phosphorylation and …
Mechanistic insights into mammalian stress granule dynamics
The accumulation of stalled translation preinitiation complexes (PICs) mediates the
condensation of stress granules (SGs). Interactions between prion-related domains and …
condensation of stress granules (SGs). Interactions between prion-related domains and …
Stress granules and cell signaling: more than just a passing phase?
Stress granules (SGs) contain translationally-stalled mRNAs, associated preinitiation factors,
and specific RNA-binding proteins. In addition, many signaling proteins are recruited to SGs …
and specific RNA-binding proteins. In addition, many signaling proteins are recruited to SGs …
Stress granules, P-bodies and cancer
Cancer cells are exposed to adverse conditions in the tumor microenvironment, and utilize
post-transcriptional control mechanisms to re-program gene expression in ways that …
post-transcriptional control mechanisms to re-program gene expression in ways that …