Functional metagenomics as a tool for identification of new antibiotic resistance genes from natural environments
Antibiotic resistance has become a major concern for human and animal health, as
therapeutic alternatives to treat multidrug-resistant microorganisms are rapidly dwindling …
therapeutic alternatives to treat multidrug-resistant microorganisms are rapidly dwindling …
ResFinderFG v2. 0: a database of antibiotic resistance genes obtained by functional metagenomics
Metagenomics can be used to monitor the spread of antibiotic resistance genes (ARGs).
ARGs found in databases such as ResFinder and CARD primarily originate from culturable …
ARGs found in databases such as ResFinder and CARD primarily originate from culturable …
[HTML][HTML] Early genetic diagnosis of clarithromycin resistance in Helicobacter pylori
XH Li, YY Huang, LM Lu, LJ Zhao, XK Luo… - World Journal of …, 2021 - ncbi.nlm.nih.gov
BACKGROUND The drug resistance rate of clinical Helicobacter pylori (H. pylori) isolates
has increased. However, the mechanism of drug resistance remains unclear. In this study …
has increased. However, the mechanism of drug resistance remains unclear. In this study …
[HTML][HTML] The Prevalence and the Underlying Mechanisms of Fosfomycin Resistance of Escherichia coli and Salmonella spp. Among Cattle in Japan
Y Hosoi, M Kawanishi, S Harada, M Kumakawa… - International Journal of …, 2024 - mdpi.com
To investigate fosfomycin resistance rates in cattle across Japan, we carried out
susceptibility tests. To identify the genes contributing to fosfomycin resistance, we performed …
susceptibility tests. To identify the genes contributing to fosfomycin resistance, we performed …
Novel soil-derived beta-lactam, chloramphenicol, fosfomycin and trimethoprim resistance genes revealed by functional metagenomics
IM Willms, M Grote, M Kocatürk, L Singhoff, AA Kraft… - Antibiotics, 2021 - mdpi.com
Antibiotic resistance genes (ARGs) in soil are considered to represent one of the largest
environmental resistomes on our planet. As these genes can potentially be disseminated …
environmental resistomes on our planet. As these genes can potentially be disseminated …
Novel biological resources screened from uncultured bacteria by a metagenomic method
N Kimura - Metagenomics, 2018 - Elsevier
Microbial genome analysis has revealed numerous gene sequences, with the potential to
code the enzymes for using in an industrial, agricultural and pharmaceutical application …
code the enzymes for using in an industrial, agricultural and pharmaceutical application …
Discovery of a new polyhydroxyalkanoate synthase from limestone soil through metagenomic approach
PHA synthase (PhaC) is the key enzyme in the production of biodegradable plastics known
as polyhydroxyalkanoate (PHA). Nevertheless, most of these enzymes are isolated from …
as polyhydroxyalkanoate (PHA). Nevertheless, most of these enzymes are isolated from …
QM/MM study of the fosfomycin resistance mechanism involving FosB enzyme
Multidrug-resistant organisms contain antibiotic-modifying enzymes that facilitate resistance
to a variety of antimicrobial compounds. Particularly, the fosfomycin (FOF) drug can be …
to a variety of antimicrobial compounds. Particularly, the fosfomycin (FOF) drug can be …
Computed insight into a peptide inhibitor preventing the induced fit mechanism of MurA enzyme from Pseudomonas aeruginosa
UDP‐N‐acetylglucosamine enolpyruvyl transferase (MurA) is one of the key enzymes
involved in peptidoglycan biosynthesis. The peptide HESFWYLPHQSY (called PEP 1354) is …
involved in peptidoglycan biosynthesis. The peptide HESFWYLPHQSY (called PEP 1354) is …
Whole Genome Sequencing of Levilactobacillus brevis HQ1-1 for Understanding the Characteristics of Its Antibiotic Resistance Genes
QH Wu, DD Li, SCL Wu, Y San, Q **ng, H Hu… - Microbiology, 2023 - Springer
Lactic acid bacteria (LAB) are the most commonly used microorganisms in fermented foods.
Currently, in the context of antibiotic resistance (AR), the safe use of LAB has attracted more …
Currently, in the context of antibiotic resistance (AR), the safe use of LAB has attracted more …