The sequence of the human genome
A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human
genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion …
genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion …
Exploring the new world of the genome with DNA microarrays
PO Brown, D Botstein - Nature genetics, 1999 - nature.com
Thousands of genes are being discovered for the first time by sequencing the genomes of
model organisms, an exhilarating reminder that much of the natural world remains to be …
model organisms, an exhilarating reminder that much of the natural world remains to be …
Initial sequencing and analysis of the human genome
US DOE Joint Genome Institute: Hawkins Trevor 4 … - Nature, 2001 - nature.com
The human genome holds an extraordinary trove of information about human development,
physiology, medicine and evolution. Here we report the results of an international …
physiology, medicine and evolution. Here we report the results of an international …
The human genome browser at UCSC
As vertebrate genome sequences near completion and research refocuses to their analysis,
the issue of effective genome annotation display becomes critical. A mature web tool for …
the issue of effective genome annotation display becomes critical. A mature web tool for …
Finishing the euchromatic sequence of the human genome
International Human Genome Sequencing Consortium - Nature, 2004 - nature.com
The sequence of the human genome encodes the genetic instructions for human
physiology, as well as rich information about human evolution. In 2001, the International …
physiology, as well as rich information about human evolution. In 2001, the International …
Mutations in SDHD, a Mitochondrial Complex II Gene, in Hereditary Paraganglioma
BE Baysal, RE Ferrell, JE Willett-Brozick, EC Lawrence… - Science, 2000 - science.org
Hereditary paraganglioma (PGL) is characterized by the development of benign,
vascularized tumors in the head and neck. The most common tumor site is the carotid body …
vascularized tumors in the head and neck. The most common tumor site is the carotid body …
[HTML][HTML] Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes
MF McDermott, I Aksentijevich, J Galon, EM McDermott… - Cell, 1999 - cell.com
Autosomal dominant periodic fever syndromes are characterized by unexplained episodes
of fever and severe localized inflammation. In seven affected families, we found six different …
of fever and severe localized inflammation. In seven affected families, we found six different …
A hypercube-based encoding for evolving large-scale neural networks
Research in neuroevolution—that is, evolving artificial neural networks (ANNs) through
evolutionary algorithms—is inspired by the evolution of biological brains, which can contain …
evolutionary algorithms—is inspired by the evolution of biological brains, which can contain …
Genome-wide analysis of DNA copy-number changes using cDNA microarrays
Gene amplifications and deletions frequently contribute to tumorigenesis. Characterization
of these DNA copy-number changes is important for both the basic understanding of cancer …
of these DNA copy-number changes is important for both the basic understanding of cancer …
The DNA sequence of human chromosome 21
Chromosome 21 is the smallest human autosome. An extra copy of chromosome 21 causes
Down syndrome, the most frequent genetic cause of significant mental retardation, which …
Down syndrome, the most frequent genetic cause of significant mental retardation, which …