Mechanochemistry: opportunities for new and cleaner synthesis

SL James, CJ Adams, C Bolm, D Braga… - Chemical Society …, 2012 - pubs.rsc.org
The aim of this critical review is to provide a broad but digestible overview of
mechanochemical synthesis, ie reactions conducted by grinding solid reactants together …

[HTML][HTML] Pharmaceutical cocrystals: A review of preparations, physicochemical properties and applications

M Guo, X Sun, J Chen, T Cai - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Pharmaceutical cocrystals are multicomponent systems in which at least one component is
an active pharmaceutical ingredient and the others are pharmaceutically acceptable …

Creating cocrystals: A review of pharmaceutical cocrystal preparation routes and applications

M Karimi-Jafari, L Padrela, GM Walker… - Crystal Growth & …, 2018 - ACS Publications
Originally discovered almost a century ago, cocrystals continue to gain interest in the
modern day due to their ability to modify the physical properties of solid-state materials …

Frequency selective fingerprint sensor: the Terahertz unity platform for broadband chiral enantiomers multiplexed signals and narrowband molecular AIT …

J Lyu, S Shen, L Chen, Y Zhu, S Zhuang - PhotoniX, 2023 - Springer
Chiral enantiomers have different pharmacological and pharmacokinetic characteristics. It is
important to strictly detect chiral component for avoiding being harmful to the human body …

Metal–organic frameworks meet scalable and sustainable synthesis

PA Julien, C Mottillo, T Friščić - Green Chemistry, 2017 - pubs.rsc.org
Over the past decade, metal–organic frameworks (MOFs) have emerged as enabling
materials for a wide variety of sustainable technologies, leading to their recent …

Dynamic disorder, phonon lifetimes, and the assignment of modes to the vibrational spectra of methylammonium lead halide perovskites

AMA Leguy, AR Goñi, JM Frost, J Skelton… - Physical Chemistry …, 2016 - pubs.rsc.org
We present Raman and terahertz absorbance spectra of methylammonium lead halide
single crystals (MAPbX3, X= I, Br, Cl) at temperatures between 80 and 370 K. These results …

Real-time and in situ monitoring of mechanochemical milling reactions

T Friščić, I Halasz, PJ Beldon, AM Belenguer… - Nature …, 2013 - nature.com
Chemical and structural transformations have long been carried out by milling. Such
mechanochemical steps are now ubiquitous in a number of industries (such as the …

Supramolecular concepts and new techniques in mechanochemistry: cocrystals, cages, rotaxanes, open metal–organic frameworks

T Friščić - Chemical Society Reviews, 2012 - pubs.rsc.org
Mechanochemical reactions effected by milling or grinding are an attractive means to
conduct chemical reactions dependent on molecular recognition and to systematically …

Recent advances in understanding the mechanism of cocrystal formation via grinding

T Friscic, W Jones - Crystal Growth and Design, 2009 - ACS Publications
A brief and systematic overview of recent advances in understanding the mechanism of
mechanochemical cocrystallization at macroscopic (bulk phase transformations) and …

Towards medicinal mechanochemistry: evolution of milling from pharmaceutical solid form screening to the synthesis of active pharmaceutical ingredients (APIs)

D Tan, L Loots, T Friščić - Chemical Communications, 2016 - pubs.rsc.org
This overview highlights the emergent area of mechanochemical reactions for making active
pharmaceutical ingredients (APIs), and covers the latest advances in the recently …