A synopsis on aging—Theories, mechanisms and future prospects
Answering the question as to why we age is tantamount to answering the question of what is
life itself. There are countless theories as to why and how we age, but, until recently, the very …
life itself. There are countless theories as to why and how we age, but, until recently, the very …
Common methods of biological age estimation
L Jia, W Zhang, X Chen - Clinical interventions in aging, 2017 - Taylor & Francis
At present, no single indicator could be used as a golden index to estimate aging process.
The biological age (BA), which combines several important biomarkers with mathematical …
The biological age (BA), which combines several important biomarkers with mathematical …
Towards a comprehensive public health response to population ageing
Worldwide, populations are rapidly ageing. This demographic shift presents both
opportunities and challenges. Most people aspire to live a long and healthy life, and older …
opportunities and challenges. Most people aspire to live a long and healthy life, and older …
Aging with HIV
G Guaraldi, J Milic, C Mussini - Current HIV/AIDS Reports, 2019 - Springer
Abstract Purpose of Review This review points out unmet medical needs and open research
questions of older adults living with HIV. Starting from the definition of aging in HIV, it …
questions of older adults living with HIV. Starting from the definition of aging in HIV, it …
Age-related inflammation: the contribution of different organs, tissues and systems. How to face it for therapeutic approaches
E Cevenini, C Caruso, G Candore… - Current …, 2010 - ingentaconnect.com
A typical feature of ageing is a chronic, low-grade inflammation characterized by a general
increase in the production of proinflammatory cytokines and inflammatory markers (“inflamm …
increase in the production of proinflammatory cytokines and inflammatory markers (“inflamm …
Sphingosine kinases and sphingosine 1-phosphate receptors: signaling and actions in the cardiovascular system
The sphingosine kinases 1 and 2 (SphK1 and 2) catalyze the phosphorylation of the lipid,
sphingosine, generating the signal transmitter, sphingosine 1-phosphate (S1P). The …
sphingosine, generating the signal transmitter, sphingosine 1-phosphate (S1P). The …
Thermal comfort modelling of older people living in care homes: An evaluation of heat balance, adaptive comfort, and thermographic methods
Older adults are more thermally vulnerable than the younger adults that comfort metrics tend
to be empirically drawn from. They are less able to discriminate between warmth and cold …
to be empirically drawn from. They are less able to discriminate between warmth and cold …
Low grade inflammation as a common pathogenetic denominator in age-related diseases: novel drug targets for anti-ageing strategies and successful ageing …
G Candore, C Caruso, E Jirillo… - Current …, 2010 - ingentaconnect.com
Nowadays, people are living much longer than they used to do, however they are not free
from ageing. Ageing, an inexorable intrinsic process that affects all cells, tissues, organs and …
from ageing. Ageing, an inexorable intrinsic process that affects all cells, tissues, organs and …
The role of matrix metalloproteinases (MMP‐2 and MMP‐9) in ageing and longevity: Focus on sicilian long‐living individuals (LLIs)
P Cancemi, A Aiello, G Accardi… - Mediators of …, 2020 - Wiley Online Library
Extracellular matrix metalloproteinases (MMPs) are a group of proteins that activate
substrates by enzymatic cleavage and, on the basis of their activities, have been …
substrates by enzymatic cleavage and, on the basis of their activities, have been …
Health disparities: Intracellular consequences of social determinants of health
Health disparities exist dependent on socioeconomic status, living conditions, race/ethnicity,
diet, and exposures to environmental pollutants. Herein, the various exposures contributing …
diet, and exposures to environmental pollutants. Herein, the various exposures contributing …