Leucine-rich repeats (LRRs) are 20–29-residue sequence motifs present in a number of
proteins with diverse functions. The primary function of these motifs appears to be to provide …

Reproduction cannot take place without the proper functioning of the lutropin/
choriogonadotropin receptor (LHR). When the LHR does not work properly, ovulation does …

The recent unraveling of structures of genes for the gonadotropin subunits and gonadotropin
receptors has provided reproductive endocrinologists with new tools to study normal and …

The superfamily of G-protein-coupled receptors (GPCRs) could be subclassified into 7
families (A, B, large N-terminal family B-7 transmembrane helix, C, Frizzled/Smoothened …

Follicle-stimulating hormone (FSH) is central to reproduction in mammals. It acts through a G-
protein-coupled receptor on the surface of target cells to stimulate testicular and ovarian …

This review focuses on recent advances in the structure-function relationships of thyroid-
stimulating hormone (TSH) and its receptor. TSH is a member of the glycoprotein hormone …

The superfamily of leucine-rich repeat proteins can be subdivided into at least six
subfamilies, characterised by different lengths and consensus sequences of the repeats. It …

▪ Abstract The luteinizing hormone receptor (LHR) is a member of the subfamily of
glycoprotein hormone receptors within the superfamily of G protein–coupled receptor …

This article reviews the progress made in the field of glycoprotein hormones (GPH) and their
receptors (GPHR) by several groups of structural biologists including ourselves aiming to …

In glycoprotein hormone receptors, a subfamily of rhodopsin-like G protein-coupled
receptors, the recognition and activation steps are carried out by separate domains of the …