A narrative review on plasminogen activator inhibitor-1 and its (patho) physiological role: to target or not to target?
M Sillen, PJ Declerck - International journal of molecular sciences, 2021 - mdpi.com
Plasminogen activator inhibitor-1 (PAI-1) is the main physiological inhibitor of plasminogen
activators (PAs) and is therefore an important inhibitor of the plasminogen/plasmin system …
activators (PAs) and is therefore an important inhibitor of the plasminogen/plasmin system …
Choroid plexus pathophysiology
This review examines the crucial roles of the choroid plexus (ChP) in central nervous system
(CNS) pathology, emphasizing its involvement in disease mechanisms and therapeutic …
(CNS) pathology, emphasizing its involvement in disease mechanisms and therapeutic …
[HTML][HTML] Human pluripotent stem cell-derived neural cells and brain organoids reveal SARS-CoV-2 neurotropism predominates in choroid plexus epithelium
Neurological complications are common in patients with COVID-19. Although severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal pathogen of COVID-19, has …
respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal pathogen of COVID-19, has …
Choroid plexus enlargement in inflammatory multiple sclerosis: 3.0-T MRI and translocator protein PET evaluation
Background Choroid plexuses (CPs) have been suggested as a key gateway for
inflammation in experimental autoimmune encephalitis, but in vivo evidence of their …
inflammation in experimental autoimmune encephalitis, but in vivo evidence of their …
Multiple sclerosis: inflammatory and neuroglial aspects
G Papiri, G D'Andreamatteo, G Cacchiò, S Alia… - Current Issues in …, 2023 - mdpi.com
Multiple sclerosis (MS) represents the most common acquired demyelinating disorder of the
central nervous system (CNS). Its pathogenesis, in parallel with the well-established role of …
central nervous system (CNS). Its pathogenesis, in parallel with the well-established role of …
Choroid plexus volume in multiple sclerosis predicts expansion of chronic lesions and brain atrophy
Objectives Recent studies suggested that the expansion of long‐standing multiple sclerosis
(MS) lesions and an enlargement of choroid plexus may be linked to chronic inflammation …
(MS) lesions and an enlargement of choroid plexus may be linked to chronic inflammation …
Deconstructing the functional neuroanatomy of the choroid plexus: an ontogenetic perspective for studying neurodevelopmental and neuropsychiatric disorders
BKY Bitanihirwe, P Lizano, TUW Woo - Molecular Psychiatry, 2022 - nature.com
The choroid plexus (CP) is a delicate and highly vascularized structure in the brain
comprised of a dense network of fenestrated capillary loops that help in the synthesis …
comprised of a dense network of fenestrated capillary loops that help in the synthesis …
Oncostatin M triggers brain inflammation by compromising blood–brain barrier integrity
D Hermans, E Houben, P Baeten, H Slaets… - Acta …, 2022 - Springer
Oncostatin M (OSM) is an IL-6 family member which exerts neuroprotective and
remyelination-promoting effects after damage to the central nervous system (CNS) …
remyelination-promoting effects after damage to the central nervous system (CNS) …
Choroid plexus function in neurological homeostasis and disorders: The awakening of the circadian clocks and orexins
As research regarding the role of circadian rhythms, sleep, and the orexinergic system in
neurodegenerative diseases is growing, it is surprising that the choroid plexus (CP) remains …
neurodegenerative diseases is growing, it is surprising that the choroid plexus (CP) remains …
Enlarged choroid plexus related to iron rim lesions and deep gray matter atrophy in relapsing-remitting multiple sclerosis
X Wang, Q Zhu, Z Yan, Z Shi, Y Xu, Y Liu, Y Li - Multiple Sclerosis and …, 2023 - Elsevier
Background Choroid plexus (CP) is considered to be linked to inflammation of multiple
sclerosis (MS), but its connection with markers of inflammation in vivo in MS is unclear, the …
sclerosis (MS), but its connection with markers of inflammation in vivo in MS is unclear, the …