Prognostic biomarkers in oral squamous cell carcinoma: a systematic review
Over the years, several tumor biomarkers have been suggested to foresee the prognosis
oral squamous cell carcinoma (OSCC) patients. Here, we present a systematic review to …
oral squamous cell carcinoma (OSCC) patients. Here, we present a systematic review to …
Targeting Cdc20 as a novel cancer therapeutic strategy
Abstract The Anaphase Promoting Complex (APC, also called APC/C) regulates cell cycle
progression by forming two closely related, but functionally distinct E3 ubiquitin ligase sub …
progression by forming two closely related, but functionally distinct E3 ubiquitin ligase sub …
Targeting Cdc20 for cancer therapy
Abstract The Anaphase-Promoting Complex/Cyclosome (APC/C), an E3 ubiquitin ligase,
and two co-activators, Cdc20 and Cdh1, enable the ubiquitin-dependent proteasomal …
and two co-activators, Cdc20 and Cdh1, enable the ubiquitin-dependent proteasomal …
Upregulation of BUB1B, CCNB1, CDC7, CDC20, and MCM3 in tumor tissues predicted worse overall survival and disease‐free survival in hepatocellular carcinoma …
L Zhuang, Z Yang, Z Meng - BioMed research international, 2018 - Wiley Online Library
Objective. To evaluate the association between upregulated differentially expressed genes
(DEGs) and the outcomes of patients with hepatocellular carcinoma (HCC). Methods. Using …
(DEGs) and the outcomes of patients with hepatocellular carcinoma (HCC). Methods. Using …
Cdc20: at the crossroads between chromosome segregation and mitotic exit
M Kapanidou, NL Curtis, VM Bolanos-Garcia - Trends in biochemical …, 2017 - cell.com
Cell-division cycle protein 20 homologue (Cdc20) has important functions in chromosome
segregation and mitotic exit. Cdc20 is the target of the spindle assembly checkpoint (SAC) …
segregation and mitotic exit. Cdc20 is the target of the spindle assembly checkpoint (SAC) …
[HTML][HTML] Increased CDC20 expression is associated with development and progression of hepatocellular carcinoma
J Li, JZ Gao, JL Du, ZX Huang… - … journal of oncology, 2014 - spandidos-publications.com
Abstract Cell division cycle 20 (CDC20) encodes a regulatory protein interacting with the
anaphase-promoting complex/cyclosome (APC/C) in the cell cycle and plays important roles …
anaphase-promoting complex/cyclosome (APC/C) in the cell cycle and plays important roles …
Cdc20 and securin overexpression predict short-term breast cancer survival
H Karra, H Repo, I Ahonen, E Löyttyniemi… - British journal of …, 2014 - nature.com
Background: Cdc20 is an essential component of cell division and responsible for anaphase
initiation regulated by securin degradation. Cdc20 function is strongly regulated by the …
initiation regulated by securin degradation. Cdc20 function is strongly regulated by the …
Aneuploidy: Cancer strength or vulnerability?
Aneuploidy is a very rare and tissue‐specific event in normal conditions, occurring in a low
number of brain and liver cells. Its frequency increases in age‐related disorders and is one …
number of brain and liver cells. Its frequency increases in age‐related disorders and is one …
Integrated bioinformatics analysis for the screening of hub genes and therapeutic drugs in ovarian cancer
D Yang, Y He, B Wu, Y Deng, N Wang, M Li… - Journal of ovarian …, 2020 - Springer
Background Ovarian cancer (OC) ranks fifth as a cause of gynecological cancer-associated
death globally. Until now, the molecular mechanisms underlying the tumorigenesis and …
death globally. Until now, the molecular mechanisms underlying the tumorigenesis and …
Cell division cycle 20 (CDC20) drives prostate cancer progression via stabilization of β-catenin in cancer stem-like cells
Q Zhang, H Huang, A Liu, J Li, C Liu, B Sun, L Chen… - …, 2019 - thelancet.com
Background Cell division cycle 20 (CDC20) is frequently overexpressed in malignant
tumours and involved in the differentiation process of hematopoietic stem cells. However …
tumours and involved in the differentiation process of hematopoietic stem cells. However …