Ki-67: more than a proliferation marker

X Sun, PD Kaufman - Chromosoma, 2018 - Springer
Ki-67 protein has been widely used as a proliferation marker for human tumor cells for
decades. In recent studies, multiple molecular functions of this large protein have become …

[HTML][HTML] Prognostic biomarkers of cell proliferation in colorectal cancer (CRC): From immunohistochemistry to molecular biology techniques

A Kasprzak - Cancers, 2023 - mdpi.com
Simple Summary This review aims to shed light on the proliferative markers important in the
everyday clinical management of colorectal cancer (CRC), ranging from simple methods of …

Differential functions of splicing factors in mammary transformation and breast cancer metastasis

SH Park, M Brugiolo, M Akerman, S Das, L Urbanski… - Cell reports, 2019 - cell.com
Misregulation of alternative splicing is a hallmark of human tumors, yet to what extent and
how it contributes to malignancy are only beginning to be unraveled. Here, we define which …

Ki-67: more hidden behind a 'classic proliferation marker'

RS Gil, P Vagnarelli - Trends in biochemical sciences, 2018 - Elsevier
Nuclear antigen Ki-67 is widely accepted as a cell proliferation marker in both research and
cancer diagnostic settings. Despite its extensive use and clinical value, very little is still …

Augmented expression of Ki-67 is correlated with clinicopathological characteristics and prognosis for lung cancer patients: an up-dated systematic review and meta …

D Wei, W Chen, R Meng, N Zhao, X Zhang, D Liao… - Respiratory …, 2018 - Springer
Background Lung cancer ranks as the leading cause of cancer-related deaths worldwide
and we performed this meta-analysis to investigate eligible studies and determine the …

A comparative study of the neural stem cell niche in the adult hypothalamus of human, mouse, rat and gray mouse lemur (Microcebus murinus)

G Pellegrino, C Trubert, J Terrien… - Journal of …, 2018 - Wiley Online Library
The adult brain contains niches of neural stem cells that continuously add new neurons to
selected circuits throughout life. Two niches have been extensively studied in various …

Ki-67/MKI67 as a predictive biomarker for clinical outcome in gastric cancer patients: an updated meta-analysis and systematic review involving 53 studies and 7078 …

D **ong, C Zeng, L Jiang, D Luo, G Chen - Journal of Cancer, 2019 - pmc.ncbi.nlm.nih.gov
Gastric cancer (GC) threatens human health worldwide and we performed this meta-
analysis to evaluate the clinical value of Ki-67/MKI67 in patients with GC. The combined …

[HTML][HTML] Synthesis of cinnamic acid ester derivatives with antiproliferative and antimetastatic activities on murine melanoma cells

JA do Vale, MP Rodrigues, ÂMA Lima… - Biomedicine & …, 2022 - Elsevier
Melanoma is the most aggressive skin cancer, and its incidence has continued to rise during
the past decades. Conventional treatments present severe side effects in cancer patients …

[HTML][HTML] A genome-scale CRISPR screen reveals PRMT1 as a critical regulator of androgen receptor signaling in prostate cancer

S Tang, V Sethunath, NY Metaferia, MF Nogueira… - Cell reports, 2022 - cell.com
Androgen receptor (AR) signaling is the central driver of prostate cancer across disease
states. While androgen deprivation therapy (ADT) is effective in the initial treatment of …

Ag2[Fe(CN)5NO] Nanoparticles Exhibit Antibacterial Activity and Wound Healing Properties

BR Rao, R Kotcherlakota, SK Nethi… - ACS Biomaterials …, 2018 - ACS Publications
Therapeutic agents harboring both wound healing and antibacterial activities have much
demand in biomedical applications. Development of such candidates with clinically …