Single-pass membrane receptors contain extracellular domains that respond to external
stimuli and transmit information to intracellular domains through a single transmembrane …

Supramolecular self‐assembling peptide systems are attracting increasing interest in the
field of cancer theranostics. Additionally, transformation of the immunologically cold tumor …

Chemotherapeutic agents have been used extensively in breast cancer remedy. However,
most anticancer drugs cannot differentiate between cancer cells and normal cells, leading to …

The EphA2 receptor tyrosine kinase is capable of activating multiple diverse signaling
pathways with roles in processes such as tissue homeostasis and cancer. EphA2 is known …

FRET is an indispensable experimental tool for studying membrane proteins. Currently, two
models are available for researchers to determine the oligomerization state of membrane …

The receptor tyrosine kinase (RTK) EphA2 is expressed in epithelial and endothelial cells
and controls the assembly of cell–cell junctions. EphA2 has also been implicated in many …

Cadherins are essential adhesion proteins that regulate tissue cohesion and paracellular
permeability by assembling dense adhesion plaques at cell-to-cell contacts. Adherens …

Ligand binding induces extensive spatial reorganization and clustering of the EphA2
receptor at the cell membrane. It has previously been shown that the nanoscale spatial …

Receptor tyrosine kinases (RTKs) are cell surface receptors which control cell growth and
differentiation, and play important roles in tumorigenesis. Despite decades of RTK research …

EphA2 is an important oncogenic protein and emerging drug target, but the oncogenic role
and mechanism of ligand-independent phosphorylation of EphA2 at tyrosine 772 (pY772 …