Recurrent pregnancy loss etiology, risk factors, diagnosis, and management. Fresh look into a full box

A Turesheva, G Aimagambetova, T Ukybassova… - Journal of clinical …, 2023 - mdpi.com
Recurrent pregnancy loss is a complex health challenge with no universally accepted
definition. Inconsistency in definitions involves not only the number of spontaneous …

[HTML][HTML] Clinical relevance of vaginal and endometrial microbiome investigation in women with repeated implantation failure and recurrent pregnancy loss

X Gao, YV Louwers, JSE Laven… - International Journal of …, 2024 - mdpi.com
Recent studies have investigated if and how the vaginal and endometrial microbiome might
affect endometrial receptivity and reproductive health. Although there is no consensus on …

Good practice recommendations on add-ons in reproductive medicine

ESHRE Add-Ons Working Group, K Lundin… - Human …, 2023 - academic.oup.com
STUDY QUESTION Which add-ons are safe and effective to be used in ART treatment?
SUMMARY ANSWER Forty-two recommendations were formulated on the use of add-ons in …

ESHRE good practice recommendations on recurrent implantation failure

ESHRE Working Group on Recurrent … - Human …, 2023 - academic.oup.com
STUDY QUESTION How should recurrent implantation failure (RIF) in patients undergoing
ART be defined and managed? SUMMARY ANSWER This is the first ESHRE good practice …

Heparin for women with recurrent miscarriage and inherited thrombophilia (ALIFE2): an international open-label, randomised controlled trial

S Quenby, K Booth, L Hiller, A Coomarasamy… - The Lancet, 2023 - thelancet.com
Background Anticoagulant therapy might reduce the number of miscarriages and adverse
pregnancy outcomes in women with recurrent pregnancy loss and inherited thrombophilia …

[HTML][HTML] The diagnostics and treatment of recurrent pregnancy loss

J Tomkiewicz, D Darmochwał-Kolarz - Journal of clinical medicine, 2023 - mdpi.com
Recurrent pregnancy loss is a common problem in the reproductive age population of
women. It can be caused by many different conditions. This problem is addressed in …

[HTML][HTML] Immunologic insights in recurrent spontaneous abortion: Molecular mechanisms and therapeutic interventions

D Guan, W Sun, M Gao, Z Chen, X Ma - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Recurrent spontaneous abortion refers to the occurrence of two or more spontaneous
abortions before or during the early stages of pregnancy. The immune system plays a crucial …

[HTML][HTML] The microbiome in recurrent pregnancy loss–A sco** review

K Vomstein, MC Krog, T Wrønding… - Journal of reproductive …, 2024 - Elsevier
Recurrent pregnancy loss (RPL) is a troubling condition that affects couples worldwide.
Despite extensive research efforts, many RPL cases remain unexplained, highlighting the …

[HTML][HTML] Genetic causes of sporadic and recurrent miscarriage

P Melo, R Dhillon-Smith, MA Islam, A Devall… - Fertility and …, 2023 - Elsevier
Approximately 80% of miscarriages happen within the first 12 weeks of gestation. More than
half of early losses result from genetic defects, usually presenting as abnormal chromosome …

Low-molecular-weight heparin in the prevention of unexplained recurrent miscarriage: A systematic review and meta-analysis

M Scarrone, N Salmeri, G Buzzaccarini, V Canti… - Scientific Reports, 2024 - nature.com
The etiology of recurrent pregnancy loss (RPL) is complex and multifactorial and in half of
patients it remains unexplained (U-RPL). Recently, low-molecular-weight heparin (LMWH) …