Short-chain fatty acids: linking diet, the microbiome and immunity

ER Mann, YK Lam, HH Uhlig - Nature Reviews Immunology, 2024 - nature.com
The short-chain fatty acids (SCFAs) butyrate, propionate and acetate are microbial
metabolites and their availability in the gut and other organs is determined by environmental …

The evolving microbiome of dental caries

G Spatafora, Y Li, X He, A Cowan, ACR Tanner - Microorganisms, 2024 - mdpi.com
Dental caries is a significant oral and public health problem worldwide, especially in low-
income populations. The risk of dental caries increases with frequent intake of dietary …

[HTML][HTML] Current status of probiotic and related health benefits

TK Das, S Pradhan, S Chakrabarti, KC Mondal… - Applied Food …, 2022 - Elsevier
This review is aimed to explore the health beneficial effects of probiotics which are live
microorganisms that provide a positive health influence on humans when taken in sufficient …

Gut microbiota in cancer immune response and immunotherapy

CB Zhou, YL Zhou, JY Fang - Trends in cancer, 2021 - cell.com
The gastrointestinal tract (GIT) is the largest immune organ and maintains systemic immune
homeostasis in the presence of bacterial challenge. Immune elimination and immune …

Gut microbiota and colonization resistance against bacterial enteric infection

QR Ducarmon, RD Zwittink, BVH Hornung… - Microbiology and …, 2019 - journals.asm.org
The gut microbiome is critical in providing resistance against colonization by exogenous
microorganisms. The mechanisms via which the gut microbiota provide colonization …

CRISPR-Cas-based antimicrobials: design, challenges, and bacterial mechanisms of resistance

A Mayorga-Ramos, J Zúñiga-Miranda… - ACS infectious …, 2023 - ACS Publications
The emergence of antibiotic-resistant bacterial strains is a source of public health concern
across the globe. As the discovery of new conventional antibiotics has stalled significantly …

[HTML][HTML] Antibiotics-driven gut microbiome perturbation alters immunity to vaccines in humans

T Hagan, M Cortese, N Rouphael, C Boudreau… - Cell, 2019 - cell.com
Emerging evidence indicates a central role for the microbiome in immunity. However, causal
evidence in humans is sparse. Here, we administered broad-spectrum antibiotics to healthy …

Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistance

SW Dickey, GYC Cheung, M Otto - Nature Reviews Drug Discovery, 2017 - nature.com
The rapid evolution and dissemination of antibiotic resistance among bacterial pathogens
are outpacing the development of new antibiotics, but antivirulence agents provide an …

[HTML][HTML] Phage-encoded endolysins

F Abdelrahman, M Easwaran, OI Daramola, S Ragab… - Antibiotics, 2021 - mdpi.com
Due to the global emergence of antibiotic resistance, there has been an increase in
research surrounding endolysins as an alternative therapeutic. Endolysins are phage …

Update of probiotics in human world: A nonstop source of benefactions till the end of time

M Zommiti, MGJ Feuilloley, N Connil - Microorganisms, 2020 - mdpi.com
Lactic acid bacteria (LAB) are known for their biotechnological potential. Moreover, LAB are
distinguished by amazing criteria: Adjusting the intestinal environment, inhibiting pathogenic …