Pax6-dependent cortical glutamatergic neuronal differentiation regulates autism-like behavior in prenatally valproic acid-exposed rat offspring

KC Kim, DK Lee, HS Go, P Kim, CS Choi, JW Kim… - Molecular …, 2014 - Springer
Imbalance in excitatory/inhibitory signal in the brain has been proposed as one of the main
pathological features in autism spectrum disorders, although the underlying cellular and …

Fetal alcohol spectrum disorders and cognitive functions of young children

I Bakoyiannis, E Gkioka, V Pergialiotis… - Reviews in the …, 2014 - degruyter.com
Fetal alcohol spectrum disorder (FASD) is one of the main causes of mental retardation
worldwide. Nearly 1% of children in North America are affected from antenatal exposure to …

Probing impaired neurogenesis in human brain organoids exposed to alcohol

Y Zhu, L Wang, F Yin, Y Yu, Y Wang… - Integrative …, 2017 - academic.oup.com
The fetal brain is highly vulnerable to ethanol exposure, which can trigger various long-term
neuronal disabilities and cognitive dysfunctions. However, a comprehensive understanding …

Upregulated GIRK2 counteracts ethanol-induced changes in excitability and respiration in human neurons

I Prytkova, Y Liu, M Fernando, I Gameiro-Ros… - Journal of …, 2024 - jneurosci.org
Genome-wide association studies (GWAS) of electroencephalographic endophenotypes for
alcohol use disorder (AUD) has identified noncoding polymorphisms within the KCNJ6 …

Prenatal alcohol exposure alters expression of neurogenesis-related genes in an ex vivo cell culture model

CR Tyler, AM Allan - Alcohol, 2014 - Elsevier
Prenatal alcohol exposure can lead to long-lasting changes in functional and genetic
programs of the brain, which may underlie behavioral alterations seen in Fetal Alcohol …

Embryonic alcohol exposure promotes long-term effects on cerebral glutamate transport of adult zebrafish

S Baggio, BH Mussulini, DL de Oliveira, KC Zenki… - Neuroscience …, 2017 - Elsevier
Ethanol is a widely consumed substance throughout the world. During development it can
substantially damage the human fetus, whereas the develo** brain is particularly …