CaMKII (the multifunctional Ca2+ and calmodulin-dependent protein kinase II) is a highly
validated signal for promoting a variety of common diseases, particularly in the …

Nanomedicine integrates different functional materials to realize the customization of
carriers, aiming at increasing the cancer therapeutic efficacy and reducing the off‐target …

The first two mRNA vaccines against infection by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) that were approved by regulators require a cold chain and …

Aging-induced alternations of vasculature structures, phenotypes, and functions are key in
the occurrence and development of vascular aging-related diseases. Multiple molecular and …

Phosphorus plays an indispensable role in energy metabolism, acid-base balance, and
genetic substances transfer. As nanotechnology advances, plenty of phosphorus-based …

BACKGROUND: Exosome therapy shows potential for cardiac repair after injury. However,
intrinsic challenges such as short half-life and lack of clear targets hinder the clinical …

Cell therapy has been a promising strategy for cardiac repair after injury or infarction;
however, low retention and engraftment of transplanted cells limit potential therapeutic …

Mitochondrial dysfunction characterized by impaired bioenergetics, oxidative stress and
aldehydic load is a hallmark of heart failure. Recently, different research groups have …

Calcium phosphate is applied in many products in biomedicine, but also in toothpastes and
cosmetics. In some cases, it is present in nanoparticulate form, either on purpose or after …

Nanomedicines offer nanoscale drug delivery system. They offer ways of promising drug
transportation, and address the issues of lack of targeting and permeability of traditional …