Results of epidemiological studies have shown that chronic obstructive pulmonary disease
(COPD) is frequently associated with comorbidities, the most serious and prevalent being …

Background: Chronic obstructive pulmonary disease (COPD) is a leading cause of
morbidity, mortality, and resource use worldwide. The goal of this Official American Thoracic …

Chronic obstructive pulmonary disease (COPD) is characterized by lung inflammation that
persists after smoking cessation. This inflammation is heterogeneous but the key …

Exacerbations of chronic obstructive pulmonary disease (COPD) are important events that
carry significant consequences for patients. Some patients experience frequent …

Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality
worldwide and results in an economic and social burden that is both substantial and …

Purpose Observational studies using computerized healthcare databases have become
popular to investigate the potential effectiveness of old drugs for new indications. Many of …

The cholesterol biosynthesis pathway, also known as the mevalonate (MVA) pathway, is an
essential cellular pathway that is involved in diverse cell functions. The enzyme 3-hydroxy-3 …

Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality
worldwide. It has been projected to move from the sixth to the third most common cause of …

Chronic obstructive pulmonary disease (COPD) is characterised by minimally reversible
airflow limitation and features of systemic inflammation. Current therapies for COPD have …

BACKGROUND: Studies suggest that statins decrease mortality in COPD patients but it is
unknown which patients might benefit most. OBJECTIVES: We investigated whether statins …