Influenza viruses cause seasonal epidemics and pandemic outbreaks associated with
significant morbidity and mortality, and a huge cost. Since resistance to the existing anti …

The influenza pandemic is a major threat to human health, and highly aggressive strains
such as H1N1, H5N1 and H7N9 have emphasized the need for therapeutic strategies to …

Favipiravir was first synthesized from an inexpensive and commercially available starting
material, 2-aminopyrazine. The preferred route embedded within Scheme 4 consisted of …

Cancer is becoming more common worldwide, impacting the vast majority of people. As a
result, new anticancer drugs are currently being created, and their safety is still being …

In the first part of this overview, we described the life cycle of the influenza virus and the
pharmacological action of the currently available drugs. This second part provides an …

Among many subtypes of influenza A viruses, influenza A (H1N1) and A (H3N2) subtypes
are currently circulating among humans (WHO report 2014–15). Therapeutically, the …

Chemical modification of sugars and nucleosides has a long history of producing
compounds with improved selectivity and efficacy. In this study, several modified sugars (2 …

The UV-induced photochemistry and molecular structure of 3-aminopyrazine-2-carboxylic
acid were studied in argon matrices by Fourier-transform infrared spectroscopy and …

Phytochemical studies led to the isolation of five new sesquiterpeniod esters, named
balsamiferine NR, along with ten known compounds (6-15) from the leaves of Blumea …

Inflammation is an intricate physiological reaction that has a vital function in the body's
protection against detrimental stimuli. Nevertheless, uncontrolled inflammation may result in …