[HTML][HTML] Sleep spindles: mechanisms and functions

LMJ Fernandez, A Lüthi - Physiological reviews, 2020 - journals.physiology.org
Sleep spindles are burstlike signals in the electroencephalogram (EEG) of the slee**
mammalian brain and electrical surface correlates of neuronal oscillations in thalamus. As …

[HTML][HTML] Deep brain stimulation of thalamus for epilepsy

RS Fisher - Neurobiology of Disease, 2023 - Elsevier
Neuromodulation (neurostimulation) is a relatively new and rapidly growing treatment for
refractory epilepsy. Three varieties are approved in the US: vagus nerve stimulation (VNS) …

SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery

JJ Frere, RA Serafini, KD Pryce, M Zazhytska… - Science translational …, 2022 - science.org
The host response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection can result in prolonged pathologies collectively referred to as post-acute sequalae …

A model for focal seizure onset, propagation, evolution, and progression

J Liou, EH Smith, LM Bateman, SL Bruce… - Elife, 2020 - elifesciences.org
We developed a neural network model that can account for major elements common to
human focal seizures. These include the tonic-clonic transition, slow advance of clinical …

Decreased but diverse activity of cortical and thalamic neurons in consciousness-impairing rodent absence seizures

C McCafferty, BF Gruenbaum, R Tung, JJ Li… - Nature …, 2023 - nature.com
Absence seizures are brief episodes of impaired consciousness, behavioral arrest, and
unresponsiveness, with yet-unknown neuronal mechanisms. Here we report that an awake …

Structural and functional organization of the midline and intralaminar nuclei of the thalamus

RP Vertes, SB Linley, AKP Rojas - Frontiers in Behavioral …, 2022 - frontiersin.org
The midline and intralaminar nuclei of the thalamus form a major part of the “limbic
thalamus;” that is, thalamic structures anatomically and functionally linked with the limbic …

Advancing thalamic neuromodulation in epilepsy: Bridging adult data to pediatric care

D Samanta, G Aungaroon, GW Albert, C Karakas… - Epilepsy Research, 2024 - Elsevier
Thalamic neuromodulation has emerged as a treatment option for drug-resistant epilepsy
(DRE) with widespread and/or undefined epileptogenic networks. While deep brain …

Distinct fastigial output channels and their impact on temporal lobe seizures

ML Streng, MR Tetzlaff, E Krook-Magnuson - Journal of Neuroscience, 2021 - jneurosci.org
Despite being canonically considered a motor control structure, the cerebellum is
increasingly recognized for important roles in processes beyond this traditional framework …

Arousal and consciousness in focal seizures

H Blumenfeld - Epilepsy Currents, 2021 - journals.sagepub.com
Impaired consciousness during seizures severely affects quality of life for people with
epilepsy but the mechanisms are just beginning to be understood. Consciousness is thought …

Identifying the neural network for neuromodulation in epilepsy through connectomics and graphs

A Vetkas, J Germann, G Elias, A Loh… - Brain …, 2022 - academic.oup.com
Deep brain stimulation is a treatment option for patients with drug-resistant epilepsy. The
precise mechanism of neuromodulation in epilepsy is unknown, and biomarkers are needed …