Peptide-receptor radionuclide therapy (PRRT) with radiolabeled somatostatin analogs such
as octreotide is an effective therapy against neuroendocrine tumors. Other radiolabeled …

An Erratum has been published for this article in Medicinal Research Reviews 2004; 24: 685–
686. Small synthetic receptor‐binding peptides are the agents of choice for diagnostic …

Integrin αvβ3 plays a critical role in tumor-induced angiogenesis and metastasis and has
become a promising diagnostic indicator and therapeutic target for various solid tumors …

Cell adhesion molecules αvβ3 and αvβ5 play a pivotal role in tumor angiogenesis and
metastasis. Antiangiogenic therapy by using small peptide antagonists of αv-integrins slows …

Overexpressed neuropeptide receptors allow tumor visualization using eg radiolabeled
peptidic receptor ligands and positron emission tomography (PET) or single photon …

Tumor growth and metastasis are angiogenesis dependent. Overexpression of integrin αvβ3
in angiogenic vessels as well as various malignant human tumors suggests the potential of …

Non-invasive PET imaging of CXCR4 expression in cancer and inflammation as well as
CXCR4-targeted radioligand therapy (RLT) have recently found their way into clinical …

Background Nanobodies are single‐domain antigen binding fragments derived from
functional heavy‐chain antibodies elicited in Camelidae. They are powerful probes for …

Although 18F-FDG PET is widely used for metastatic melanoma diagnosis, it is less accurate
than desirable, particularly for small foci. Since both melanotic and amelanotic melanomas …

Targeted radionuclide therapy (TRT) is an emerging field and has the potential to become a
major pillar in effective cancer treatment. Several pharmaceuticals are already in routine use …