Skeletal muscle energy metabolism during exercise
M Hargreaves, LL Spriet - Nature metabolism, 2020 - nature.com
The continual supply of ATP to the fundamental cellular processes that underpin skeletal
muscle contraction during exercise is essential for sports performance in events lasting …
muscle contraction during exercise is essential for sports performance in events lasting …
The regulation of fat metabolism during aerobic exercise
Since the lipid profile is altered by physical activity, the study of lipid metabolism is a
remarkable element in understanding if and how physical activity affects the health of both …
remarkable element in understanding if and how physical activity affects the health of both …
Mitochondrial RNA modifications shape metabolic plasticity in metastasis
Aggressive and metastatic cancers show enhanced metabolic plasticity, but the precise
underlying mechanisms of this remain unclear. Here we show how two NOP2/Sun RNA …
underlying mechanisms of this remain unclear. Here we show how two NOP2/Sun RNA …
AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: implications for obesity
Skeletal muscle plays an important role in regulating whole-body energy expenditure given
it is a major site for glucose and lipid oxidation. Obesity and type 2 diabetes are causally …
it is a major site for glucose and lipid oxidation. Obesity and type 2 diabetes are causally …
New insights into the interaction of carbohydrate and fat metabolism during exercise
LL Spriet - Sports medicine, 2014 - Springer
Fat and carbohydrate are important fuels for aerobic exercise and there can be reciprocal
shifts in the proportions of carbohydrate and fat that are oxidized. The interaction between …
shifts in the proportions of carbohydrate and fat that are oxidized. The interaction between …
Inhibition of fatty acid translocase (FAT/CD36) palmitoylation enhances hepatic fatty acid β-oxidation by increasing its localization to mitochondria and interaction with …
S Zeng, F Wu, M Chen, Y Li, M You… - Antioxidants & redox …, 2022 - liebertpub.com
Aims: Impaired fatty acid oxidation (FAO) in mitochondria of hepatocytes causes lipid
accumulation and excessive production of reactive oxygen species (ROS) and oxidative …
accumulation and excessive production of reactive oxygen species (ROS) and oxidative …
Molecular regulation of fatty acid oxidation in skeletal muscle during aerobic exercise
This review summarizes how fatty acid (FA) oxidation is regulated in skeletal muscle during
exercise. From the available evidence it seems that acetyl-CoA availability in the …
exercise. From the available evidence it seems that acetyl-CoA availability in the …
Regulation of AMPK activation by CD36 links fatty acid uptake to β-oxidation
Increases in muscle energy needs activate AMPK and induce sarcolemmal recruitment of
the fatty acid (FA) translocase CD36. The resulting rises in FA uptake and FA oxidation are …
the fatty acid (FA) translocase CD36. The resulting rises in FA uptake and FA oxidation are …
Physiological functions of peroxisome proliferator-activated receptor β
JG Neels, PA Grimaldi - Physiological reviews, 2014 - journals.physiology.org
The peroxisome proliferator-activated receptors, PPARα, PPARβ, and PPARγ, are a family of
transcription factors activated by a diversity of molecules including fatty acids and fatty acid …
transcription factors activated by a diversity of molecules including fatty acids and fatty acid …
Exercise metabolism: fuels for the fire
M Hargreaves, LL Spriet - Cold Spring …, 2018 - perspectivesinmedicine.cshlp.org
During exercise, the supply of adenosine triphosphate (ATP) is essential for the energy-
dependent processes that underpin ongoing contractile activity. These pathways involve …
dependent processes that underpin ongoing contractile activity. These pathways involve …