Simple Summary Breast cancer is the most common cancer among women. It is estimated
that 2.3 million new cases of BC are diagnosed globally each year. Based on mRNA gene …

Pyroptosis is an inflammatory form of cell death triggered by certain inflammasomes, leading
to the cleavage of gasdermin D (GSDMD) and activation of inactive cytokines like IL-18 and …

Cancer classification aims to provide an accurate diagnosis of the disease and prediction of
tumor behavior to facilitate oncologic decision making. Traditional breast cancer …

Breast cancer is the most common cancer diagnosed in females throughout the entire world,
and it is also the primary reason why people lose their lives due to malignant tumors. The …

The breast is a dynamic organ whose response to physiological and pathophysiological
conditions alters its disease susceptibility, yet the specific effects of these clinical variables …

Breast cancer is the second leading cause of death for women worldwide. While
monotherapy (single agent) treatments have been used for many years, they are not always …

Collective cancer invasion with leader–follower organization is increasingly recognized as a
predominant mechanism in the metastatic cascade. Leader cells support cancer invasion by …

Tumors are composed of multiple cell types besides the tumor cells themselves, including
innate immune cells such as macrophages. Tumor-associated macrophages (TAMs) are a …

Cancer cells within a tumour have heterogeneous phenotypes and exhibit dynamic
plasticity. How to evaluate such heterogeneity and its impact on outcome and drug response …

Breast carcinomas can be stratified into different entities based on clinical behavior,
histologic features, and/or by biological properties. A classification of breast cancer should …