Role of the immune system in HIV-associated neuroinflammation and neurocognitive implications

S Hong, WA Banks - Brain, behavior, and immunity, 2015 - Elsevier
Individuals living with HIV who are optimally treated with combination antiretroviral therapy
(cART) can now lead an extended life. In spite of this remarkable survival benefit from viral …

Current understanding of HIV-associated neurocognitive disorders pathogenesis

P Gannon, MZ Khan, DL Kolson - Current opinion in neurology, 2011 - journals.lww.com
Prevention and treatment of HAND requires strategies aimed at suppressing CNS HIV
replication and effects of systemic and CNS inflammation in aging and substance-abusing …

[KNIHA][B] Topological data analysis for genomics and evolution: topology in biology

R Rabadán, AJ Blumberg - 2019 - books.google.com
Biology has entered the age of Big Data. The technical revolution has transformed the field,
and extracting meaningful information from large biological data sets is now a central …

Spike proteins of SARS-CoV-2 induce pathological changes in molecular delivery and metabolic function in the brain endothelial cells

ES Kim, MT Jeon, KS Kim, S Lee, S Kim, DG Kim - Viruses, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes the
coronavirus disease (COVID-19), is currently infecting millions of people worldwide and is …

Potential molecular mechanisms of chronic fatigue in long haul COVID and other viral diseases

CG Gottschalk, D Peterson, J Armstrong, K Knox… - Infectious agents and …, 2023 - Springer
Historically, COVID-19 emerges as one of the most devastating diseases of humankind,
which creates an unmanageable health crisis worldwide. Until now, this disease costs …

Role of p53 in neurodegenerative diseases

JR Chang, M Ghafouri, R Mukerjee… - Neurodegenerative …, 2012 - karger.com
Background: p53 plays an important role in many areas of cellular physiology and biology,
ranging from cellular development and differentiation to cell cycle arrest and apoptosis …

Hippocampal adult neurogenesis: Does the immune system matter?

AS de Miranda, CJ Zhang, A Katsumoto… - Journal of the …, 2017 - Elsevier
Adult hippocampal neurogenesis involves proliferation, survival, differentiation and
integration of newborn neurons into pre-existing neuronal networks. Although its functional …

The struggle of a good friend getting old: cellular senescence in viral responses and therapy

J Kohli, I Veenstra, M Demaria - EMBO reports, 2021 - embopress.org
Cellular senescence is a state of stable cell cycle arrest associated with macromolecular
alterations and secretion of pro‐inflammatory cytokines and molecules. Senescence …

[PDF][PDF] HIV-associated neurocognitive disorders (HAND)

M Daniel Elbirt, K Mahlab-Guri, S Bazalel-Rosenberg… - Isr Med Assoc J, 2015 - ima.org.il
For editorial see page 52 since the introduction of HAART (highly active antiretroviral
therapy), the course of human immunodeficiency virus (HIV) has transformed dramatically …

Natural products as anti-HIV agents and role in HIV-associated neurocognitive disorders (HAND): A brief overview

KRV Kurapati, VS Atluri, T Samikkannu… - Frontiers in …, 2016 - frontiersin.org
As the threat of Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency
Syndrome (AIDS) persists to rise, effective drug treatments are required to treat the infected …