ABSTRACT Selenoprotein GPX4 (glutathione peroxidase 4), originally known as PHGPX
(phospholipid hydroperoxide glutathione peroxidase), is the main oxidoreductase in the use …

Selenium (Se) is a naturally occurring metalloid element essential to human and animal
health in trace amounts but it is harmful in excess. Se plays a substantial role in the …

Ferroptosis is an iron-dependent cell death, which is different from apoptosis, necrosis,
autophagy, and other forms of cell death. The process of ferroptotic cell death is defined by …

Ferroptosis is a new type of cell death that was discovered in recent years and is usually
accompanied by a large amount of iron accumulation and lipid peroxidation during the cell …

The discoveries leading to our present understanding of the glutathione peroxidases (GPxs)
are recalled. The cytosolic GPx, now GPx1, was first described by Mills in 1957 and claimed …

Selenium is an essential immunonutrient which holds the human's metabolic activity with its
chemical bonds. The organic forms of selenium naturally present in human body are …

The term ferroptosis was coined in 2012 to describe an iron-dependent regulated form of
cell death caused by the accumulation of lipid-based reactive oxygen species; this type of …

Selenium is an essential micronutrient that plays a crucial role in development and a wide
variety of physiological processes including effect immune responses. The immune system …

Reactive oxygen species (ROS) are frequently produced during viral infections. Generation
of these ROS can be both beneficial and detrimental for many cellular functions. When …

Cholesterol and its metabolites (precursors and derivatives) play an important role in cancer.
In recent years, numerous studies have reported the functions of cholesterol metabolism in …