Atomic force microscopy-based mechanobiology

M Krieg, G Fläschner, D Alsteens, BM Gaub… - Nature Reviews …, 2019 - nature.com
Mechanobiology emerges at the crossroads of medicine, biology, biophysics and
engineering and describes how the responses of proteins, cells, tissues and organs to …

Age-related vascular stiffening: causes and consequences

JC Kohn, MC Lampi, CA Reinhart-King - Frontiers in genetics, 2015 - frontiersin.org
Arterial stiffening occurs with age and is closely associated with the progression of
cardiovascular disease. Stiffening is most often studied at the level of the whole vessel …

Syringe injectable electronics

J Liu, J Liu - … Nanoelectronics for Building Smart Materials, Cyborg …, 2018 - Springer
With recent advancement in nanotechnology and materials science, we have been able to
fabricate electronics on flexible, stretchable and 3D substrates to cover electrical functional …

Actin cortex mechanics and cellular morphogenesis

G Salbreux, G Charras, E Paluch - Trends in cell biology, 2012 - cell.com
The cortex is a thin, crosslinked actin network lying immediately beneath the plasma
membrane of animal cells. Myosin motors exert contractile forces in the meshwork. Because …

Investigating cell mechanics with atomic force microscopy

K Haase, AE Pelling - Journal of The Royal Society …, 2015 - royalsocietypublishing.org
Transmission of mechanical force is crucial for normal cell development and functioning.
However, the process of mechanotransduction cannot be studied in isolation from cell …

Non-contact long-range magnetic stimulation of mechanosensitive ion channels in freely moving animals

J Lee, W Shin, Y Lim, J Kim, WR Kim, H Kim, JH Lee… - Nature materials, 2021 - nature.com
Among physical stimulation modalities, magnetism has clear advantages, such as deep
penetration and untethered interventions in biological subjects. However, some of the …

Biofunctionalized magnetic-vortex microdiscs for targeted cancer-cell destruction

DH Kim, EA Rozhkova, IV Ulasov, SD Bader, T Rajh… - Nature materials, 2010 - nature.com
Nanomagnetic materials offer exciting avenues for probing cell mechanics and activating
mechanosensitive ion channels, as well as for advancing cancer therapies. Most …

[HTML][HTML] Force microscopy of nonadherent cells: a comparison of leukemia cell deformability

MJ Rosenbluth, WA Lam, DA Fletcher - Biophysical journal, 2006 - cell.com
Atomic force microscopy (AFM) has become an important tool for quantifying mechanical
properties of biological materials ranging from single molecules to cells and tissues. Current …

Physical virology

WH Roos, R Bruinsma, GJL Wuite - Nature physics, 2010 - nature.com
Viruses are nanosized, genome-filled protein containers with remarkable thermodynamic
and mechanical properties. They form by spontaneous self-assembly inside the crowded …

AFM-based analysis of human metastatic cancer cells

SE Cross, YS **, J Tondre, R Wong, JY Rao… - …, 2008 - iopscience.iop.org
Recently biomechanics of cancer cells, in particular stiffness or elasticity, has been identified
as an important factor relating to cancer cell function, adherence, motility, transformation and …