AutoDock Vina 1.2. 0: New docking methods, expanded force field, and python bindings

J Eberhardt, D Santos-Martins… - Journal of chemical …, 2021 - ACS Publications
AutoDock Vina is arguably one of the fastest and most widely used open-source programs
for molecular docking. However, compared to other programs in the AutoDock Suite, it lacks …

Accelerating AutoDock4 with GPUs and Gradient-Based Local Search

D Santos-Martins, L Solis-Vasquez… - Journal of chemical …, 2021 - ACS Publications
AutoDock4 is a widely used program for docking small molecules to macromolecular targets.
It describes ligand–receptor interactions using a physics-inspired scoring function that has …

The role of artificial intelligence in drug screening, drug design, and clinical trials

Y Wu, L Ma, X Li, J Yang, X Rao, Y Hu, J **… - Frontiers in …, 2024 - frontiersin.org
The role of computational tools in drug discovery and development is becoming increasingly
important due to the rapid development of computing power and advancements in …

Benchmarking the performance of irregular computations in AutoDock-GPU molecular docking

L Solis-Vasquez, AF Tillack, D Santos-Martins, A Koch… - Parallel computing, 2022 - Elsevier
Irregular applications can be found in different scientific fields. In computer-aided drug
design, molecular docking simulations play an important role in finding promising drug …

The AutoDock suite at 30

DS Goodsell, MF Sanner, AJ Olson, S Forli - Protein Science, 2021 - Wiley Online Library
The AutoDock suite provides a comprehensive toolset for computational ligand docking and
drug design and development. The suite builds on 30 years of methods development …

Accelerating autodock vina with gpus

S Tang, R Chen, M Lin, Q Lin, Y Zhu, J Ding, H Hu… - Molecules, 2022 - mdpi.com
AutoDock Vina is one of the most popular molecular docking tools. In the latest benchmark
CASF-2016 for comparative assessment of scoring functions, AutoDock Vina won the best …

GPU-accelerated drug discovery with docking on the summit supercomputer: Porting, optimization, and application to COVID-19 research

S LeGrand, A Scheinberg, AF Tillack… - Proceedings of the 11th …, 2020 - dl.acm.org
Protein-ligand docking is an in silico tool used to screen potential drug compounds for their
ability to bind to a given protein receptor within a drug-discovery campaign. Experimental …

High-throughput virtual laboratory for drug discovery using massive datasets

J Glaser, JV Vermaas, DM Rogers… - … Journal of High …, 2021 - journals.sagepub.com
Time-to-solution for structure-based screening of massive chemical databases for COVID-19
drug discovery has been decreased by an order of magnitude, and a virtual laboratory has …

Brief literature review and comprehensive bioinformatics analytics unravel the potential mechanism of curcumin in the treatment of periodontitis

X Huang, Y Liu, Q Wang, HM Rehman, D Horváth… - BMC Oral Health, 2023 - Springer
Objective Periodontitis is a chronic oral disease prevalent worldwide, and natural products
are recommended as adjunctive therapy due to their minor side effects. Curcumin, a widely …

Supercomputing pipelines search for therapeutics against covid-19

JV Vermaas, A Sedova, MB Baker… - … in Science & …, 2020 - ieeexplore.ieee.org
The urgent search for drugs to combat SARS-CoV-2 has included the use of
supercomputers. The use of general-purpose graphical processing units (GPUs), massive …