Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission

D Stolz, T Mkorombindo, DM Schumann, A Agusti… - The Lancet, 2022 - thelancet.com
Executive summary Despite substantial progress in reducing the global impact of many non-
communicable diseases, including heart disease and cancer, morbidity and mortality due to …

Pathogenesis of chronic obstructive pulmonary disease: understanding the contributions of gene–environment interactions across the lifespan

A Agustí, E Melén, DL DeMeo… - The lancet Respiratory …, 2022 - thelancet.com
The traditional view of chronic obstructive pulmonary disease (COPD) as a self-inflicted
disease caused by tobacco smoking in genetically susceptible individuals has been …

Organotypic vasculature: from descriptive heterogeneity to functional pathophysiology

HG Augustin, GY Koh - Science, 2017 - science.org
BACKGROUND Each organ in the human body has its own capillary bed to carry out its
distinctive and versatile functions in response to dynamically changing systemic and local …

Mesenchymal stromal cell exosomes ameliorate experimental bronchopulmonary dysplasia and restore lung function through macrophage immunomodulation

GR Willis, A Fernandez-Gonzalez… - American journal of …, 2018 - atsjournals.org
Rationale: Mesenchymal stem/stromal cell (MSC) therapies have shown promise in
preclinical models of pathologies relevant to newborn medicine, such as bronchopulmonary …

Viral bronchiolitis in children

HC Meissner - New England Journal of Medicine, 2016 - Mass Medical Soc
Viral Bronchiolitis in Children | New England Journal of Medicine Skip to main content The New
England Journal of Medicine homepage Advanced Search SEARCH The New England Journal …

Outcomes for extremely premature infants

HC Glass, AT Costarino, SA Stayer, CM Brett… - Anesthesia & …, 2015 - journals.lww.com
Premature birth is a significant cause of infant and child morbidity and mortality. In the United
States, the premature birth rate, which had steadily increased during the 1990s and early …

Bronchopulmonary dysplasia: clinical aspects and preventive and therapeutic strategies

N Principi, GM Di Pietro, S Esposito - Journal of translational medicine, 2018 - Springer
Background Bronchopulmonary dysplasia (BPD) is the result of a complex process in which
several prenatal and/or postnatal factors interfere with lower respiratory tract development …

Bronchopulmonary dysplasia: chronic lung disease of infancy and long-term pulmonary outcomes

LM Davidson, SK Berkelhamer - Journal of clinical medicine, 2017 - mdpi.com
Bronchopulmonary dysplasia (BPD) is a chronic lung disease most commonly seen in
premature infants who required mechanical ventilation and oxygen therapy for acute …

Role of Nrf2 and its activators in respiratory diseases

Q Liu, Y Gao, X Ci - Oxidative medicine and cellular longevity, 2019 - Wiley Online Library
Transcription factor nuclear factor erythroid 2‐related factor 2 (Nrf2) is a major regulator of
antioxidant response element‐(ARE‐) driven cytoprotective protein expression. The …

Short-and long-term outcomes for extremely preterm infants

RM Patel - American journal of perinatology, 2016 - thieme-connect.com
Prematurity is the leading cause of infant mortality worldwide. In developed countries,
extremely preterm infants contribute disproportionately to both neonatal and infant mortality …