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[KNYGA][B] Genome-scale algorithm design: bioinformatics in the era of high-throughput sequencing
Presenting the fundamental algorithms and data structures that power bioinformatics
workflows, this book covers a range of topics from the foundations of sequence analysis …
workflows, this book covers a range of topics from the foundations of sequence analysis …
Biphase routing scheme for optimal throughput in large-scale optical satellite networks
In the large-scale optical satellite network (LS-OSN), hundreds to thousands of low Earth
orbit (LEO) satellites will be interconnected<? TeX 2pc 0pt?> via laser links, offering global …
orbit (LEO) satellites will be interconnected<? TeX 2pc 0pt?> via laser links, offering global …
Accurate assembly of multiple RNA-seq samples with Aletsch
Motivation High-throughput RNA sequencing has become indispensable for decoding gene
activities, yet the challenge of reconstructing full-length transcripts persists. Traditional single …
activities, yet the challenge of reconstructing full-length transcripts persists. Traditional single …
Width helps and hinders splitting flows
Minimum flow decomposition (MFD) is the NP-hard problem of finding a smallest
decomposition of a network flow/circulation X on a directed graph G into weighted source-to …
decomposition of a network flow/circulation X on a directed graph G into weighted source-to …
A safety framework for flow decomposition problems via integer linear programming
Motivation Many important problems in Bioinformatics (eg assembly or multiassembly) admit
multiple solutions, while the final objective is to report only one. A common approach to deal …
multiple solutions, while the final objective is to report only one. A common approach to deal …
Efficient minimum flow decomposition via integer linear programming
Minimum flow decomposition (MFD) is an NP-hard problem asking to decompose a network
flow into a minimum set of paths (together with associated weights). Variants of it are …
flow into a minimum set of paths (together with associated weights). Variants of it are …
Minimum flow decomposition in graphs with cycles using integer linear programming
Minimum flow decomposition (MFD)--the problem of finding a minimum set of weighted
source-to-sink paths that perfectly decomposes a flow--is a classical problem in Computer …
source-to-sink paths that perfectly decomposes a flow--is a classical problem in Computer …
Accurate flow decomposition via robust integer linear programming
Minimum flow decomposition (MFD) is a common problem across various fields of Computer
Science, where a flow is decomposed into a minimum set of weighted paths. However, in …
Science, where a flow is decomposed into a minimum set of weighted paths. However, in …
Accelerating ILP solvers for Minimum Flow Decompositions through search space and dimensionality reductions
Given a flow network, the Minimum Flow Decomposition (MFD) problem is finding the
smallest possible set of weighted paths whose superposition equals the flow. It is a classical …
smallest possible set of weighted paths whose superposition equals the flow. It is a classical …
Safe Paths and Sequences for Scalable ILPs in RNA Transcript Assembly Problems
F Sena, AI Tomescu - arxiv preprint arxiv:2411.03871, 2024 - arxiv.org
A common step at the core of many RNA transcript assembly tools is to find a set of weighted
paths that best explain the weights of a DAG. While such problems easily become NP-hard …
paths that best explain the weights of a DAG. While such problems easily become NP-hard …