[KNYGA][B] Genome-scale algorithm design: bioinformatics in the era of high-throughput sequencing

V Mäkinen, D Belazzougui, F Cunial, AI Tomescu - 2023 - books.google.com
Presenting the fundamental algorithms and data structures that power bioinformatics
workflows, this book covers a range of topics from the foundations of sequence analysis …

Biphase routing scheme for optimal throughput in large-scale optical satellite networks

Y Ning, Y Zhao, A Nag, H Wang… - Journal of Optical …, 2024 - opg.optica.org
In the large-scale optical satellite network (LS-OSN), hundreds to thousands of low Earth
orbit (LEO) satellites will be interconnected<? TeX 2pc 0pt?> via laser links, offering global …

Accurate assembly of multiple RNA-seq samples with Aletsch

Q Shi, Q Zhang, M Shao - Bioinformatics, 2024 - academic.oup.com
Motivation High-throughput RNA sequencing has become indispensable for decoding gene
activities, yet the challenge of reconstructing full-length transcripts persists. Traditional single …

Width helps and hinders splitting flows

M Cáceres, M Cairo, A Grigorjew, S Khan… - ACM Transactions on …, 2024 - dl.acm.org
Minimum flow decomposition (MFD) is the NP-hard problem of finding a smallest
decomposition of a network flow/circulation X on a directed graph G into weighted source-to …

A safety framework for flow decomposition problems via integer linear programming

FHC Dias, M Cáceres, L Williams, B Mumey… - …, 2023 - academic.oup.com
Motivation Many important problems in Bioinformatics (eg assembly or multiassembly) admit
multiple solutions, while the final objective is to report only one. A common approach to deal …

Efficient minimum flow decomposition via integer linear programming

FHC Dias, L Williams, B Mumey… - Journal of Computational …, 2022 - liebertpub.com
Minimum flow decomposition (MFD) is an NP-hard problem asking to decompose a network
flow into a minimum set of paths (together with associated weights). Variants of it are …

Minimum flow decomposition in graphs with cycles using integer linear programming

FHC Dias, L Williams, B Mumey, AI Tomescu - arxiv preprint arxiv …, 2022 - arxiv.org
Minimum flow decomposition (MFD)--the problem of finding a minimum set of weighted
source-to-sink paths that perfectly decomposes a flow--is a classical problem in Computer …

Accurate flow decomposition via robust integer linear programming

FHC Dias, AI Tomescu - IEEE/ACM Transactions on …, 2024 - ieeexplore.ieee.org
Minimum flow decomposition (MFD) is a common problem across various fields of Computer
Science, where a flow is decomposed into a minimum set of weighted paths. However, in …

Accelerating ILP solvers for Minimum Flow Decompositions through search space and dimensionality reductions

A Grigorjew, FHC Dias, A Cracco, R Rizzi… - arxiv preprint arxiv …, 2023 - arxiv.org
Given a flow network, the Minimum Flow Decomposition (MFD) problem is finding the
smallest possible set of weighted paths whose superposition equals the flow. It is a classical …

Safe Paths and Sequences for Scalable ILPs in RNA Transcript Assembly Problems

F Sena, AI Tomescu - arxiv preprint arxiv:2411.03871, 2024 - arxiv.org
A common step at the core of many RNA transcript assembly tools is to find a set of weighted
paths that best explain the weights of a DAG. While such problems easily become NP-hard …