Even though levothyroxine sodium pentahydrate tablets have been in the market since
1955, there continue to be recalls due to sub potency. We have comprehensively reviewed …

Hypothyroidism and hyperthyroidism are one of the most frequently observed endocrine
disorders in the world. Failure to undergo timely diagnosis and treatment often results in life …

The concentration of thyroxine hormone is linked to a large variety of medical conditions,
where the best therapy is hormone substitution, through administration of levothyroxine …

In this study, direct analysis in real time-mass spectrometry (DART-MS) was assessed for the
analysis of various pharmaceutical formulations with intention to summarize possible …

Levothyroxine is a drug with a narrow therapeutic index. Changing the drug formulation
composition or switching between pharmaceutical brands can alter the bioavailability, which …

The structural elucidation of unknown pharmaceutical impurities plays an important role in
the quality control of newly developed and well-established active pharmaceutical …

Thyroxine (T 4) is one of the major thyroid hormones, which regulates cellular metabolism,
central nervous system development, body temperature, reproduction and growth. The …

For the first time, a comprehensive investigation of the impurity profile of the synthetic thyroid
API (active pharmaceutical ingredient) liothyronine sodium (LT 3 Na) was performed by …

Levothyroxine as active pharmaceutical ingredient of formulations used for the treatment of
hypothyroidism is distributed worldwide and taken by millions of people. An important issue …

This article presents the evaluation of diblock and triblock poly (ethylene glycol)-b-poly (1, 3-
trimethylene carbonate) amphiphilic copolymers (PEG-PTMCs) as excipients for the …