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Inference and applications of ancestral recombination graphs
Ancestral recombination graphs (ARGs) summarize the complex genealogical relationships
between individuals represented in a sample of DNA sequences. Their use is currently …
between individuals represented in a sample of DNA sequences. Their use is currently …
Harnessing deep learning for population genetic inference
In population genetics, the emergence of large-scale genomic data for various species and
populations has provided new opportunities to understand the evolutionary forces that drive …
populations has provided new opportunities to understand the evolutionary forces that drive …
SLiM 4: multispecies eco-evolutionary modeling
The SLiM software framework for genetically explicit forward simulation has been widely
used in population genetics. However, it has been largely restricted to modeling only a …
used in population genetics. However, it has been largely restricted to modeling only a …
On the limits of fitting complex models of population history to f-statistics
Our understanding of population history in deep time has been assisted by fitting admixture
graphs (AGs) to data: models that specify the ordering of population splits and mixtures …
graphs (AGs) to data: models that specify the ordering of population splits and mixtures …
Genomic inference of a severe human bottleneck during the Early to Middle Pleistocene transition
Population size history is essential for studying human evolution. However, ancient
population size history during the Pleistocene is notoriously difficult to unravel. In this study …
population size history during the Pleistocene is notoriously difficult to unravel. In this study …
A weakly structured stem for human origins in Africa
Despite broad agreement that Homo sapiens originated in Africa, considerable uncertainty
surrounds specific models of divergence and migration across the continent. Progress is …
surrounds specific models of divergence and migration across the continent. Progress is …
The genetics of niche-specific behavioral tendencies in an adaptive radiation of cichlid fishes
Behavior is critical for animal survival and reproduction, and possibly for diversification and
evolutionary radiation. However, the genetics behind adaptive variation in behavior are …
evolutionary radiation. However, the genetics behind adaptive variation in behavior are …
The era of the ARG: An introduction to ancestral recombination graphs and their significance in empirical evolutionary genomics
In the presence of recombination, the evolutionary relationships between a set of sampled
genomes cannot be described by a single genealogical tree. Instead, the genomes are …
genomes cannot be described by a single genealogical tree. Instead, the genomes are …
[PDF][PDF] Deep learning in population genetics
Population genetics is transitioning into a data-driven discipline thanks to the availability of
large-scale genomic data and the need to study increasingly complex evolutionary …
large-scale genomic data and the need to study increasingly complex evolutionary …
A general and efficient representation of ancestral recombination graphs
As a result of recombination, adjacent nucleotides can have different paths of genetic
inheritance and therefore the genealogical trees for a sample of DNA sequences vary along …
inheritance and therefore the genealogical trees for a sample of DNA sequences vary along …