Role of reactive oxygen species in cancer progression: molecular mechanisms and recent advancements
Reactive oxygen species (ROS) play a pivotal role in biological processes and continuous
ROS production in normal cells is controlled by the appropriate regulation between the silver …
ROS production in normal cells is controlled by the appropriate regulation between the silver …
Epigallocatechin 3-gallate: From green tea to cancer therapeutics
Abstract Epigallocatechin 3-gallate (EGCG) possesses various biological functions,
including anti-cancer and anti-inflammatory properties. EGCG is an abundant polyphenolic …
including anti-cancer and anti-inflammatory properties. EGCG is an abundant polyphenolic …
Phenotype plasticity as enabler of melanoma progression and therapy resistance
I Arozarena, C Wellbrock - Nature Reviews Cancer, 2019 - nature.com
Malignant melanoma is notorious for its inter-and intratumour heterogeneity, based on
transcriptionally distinct melanoma cell phenotypes. It is thought that these distinct …
transcriptionally distinct melanoma cell phenotypes. It is thought that these distinct …
Potential therapeutic targets of epigallocatechin gallate (EGCG), the most abundant catechin in green tea, and its role in the therapy of various types of cancer
Epigallocatechin-3-gallate (EGCG), an active compound of green tea and its role in
diseases cure and prevention has been proven. Its role in diseases management can be …
diseases cure and prevention has been proven. Its role in diseases management can be …
Cancer metastasis: the role of the extracellular matrix and the heparan sulfate proteoglycan perlecan
Cancer metastasis is the dissemination of tumor cells to new sites, resulting in the formation
of secondary tumors. This process is complex and is spatially and temporally regulated by …
of secondary tumors. This process is complex and is spatially and temporally regulated by …
Flavonoids in cancer metastasis
Metastasis represents a serious complication in the treatment of cancer. Flavonoids are
plant secondary metabolites exerting various health beneficiary effects. The effects of …
plant secondary metabolites exerting various health beneficiary effects. The effects of …
Molecular mechanisms behind ROS regulation in cancer: A balancing act between augmented tumorigenesis and cell apoptosis
ROS include hydroxyl radicals (HO.), superoxide (O2..), and hydrogen peroxide (H2O2).
ROS are typically produced under physiological conditions and play crucial roles in living …
ROS are typically produced under physiological conditions and play crucial roles in living …
Tumor microenvironment differences between primary tumor and brain metastases
B Cacho-Díaz, DR García-Botello… - Journal of Translational …, 2020 - Springer
The present review aimed to discuss contemporary scientific literature involving differences
between the tumor microenvironment (TME) in melanoma, lung cancer, and breast cancer in …
between the tumor microenvironment (TME) in melanoma, lung cancer, and breast cancer in …
[HTML][HTML] Cisplatin prevents breast cancer metastasis through blocking early EMT and retards cancer growth together with paclitaxel
Cancer growth is usually accompanied by metastasis which kills most cancer patients. Here
we aim to study the effect of cisplatin at different doses on breast cancer growth and …
we aim to study the effect of cisplatin at different doses on breast cancer growth and …
Transglutaminase-2 facilitates extracellular vesicle-mediated establishment of the metastatic niche
The ability of breast cancer cells to interconvert between epithelial and mesenchymal states
contributes to their metastatic potential. As opposed to cell autonomous effects, the impact of …
contributes to their metastatic potential. As opposed to cell autonomous effects, the impact of …