Background Exposure to endocrine disrupting chemicals (EDCs) represents a critical public
health threat. Several adverse health outcomes (eg, cancers, metabolic and neurocognitive …

Motivation Exposure to pesticides may lead to adverse health effects in human populations,
in particular vulnerable groups. The main long-term health concerns are …

Abstract Systems biology as a research field has emerged within the last few decades.
Systems biology, often defined as the antithesis of the reductionist approach, integrates …

Introduction: The high failure rate of drug candidates due to toxicity, during clinical trials, is a
critical issue in drug discovery. Network biology has become a promising approach, in this …

During the past decades, many epidemiological, toxicological and biological studies have
been performed to assess the role of environmental chemicals as potential toxicants …

Background The characterization of toxicities associated with environmental and industrial
chemicals is required for risk assessment. However, we lack the toxicological data for a …

Background: The chemical part of the exposome, including drugs, may explain the increase
of health effects with outcomes such as infertility, allergies, metabolic disorders, which …

The advent of omics technologies has enhanced significantly our capacity to interpret
mechanistically the association between environmental exposure and disease. Although …