DNA nanotechnology-enabled drug delivery systems
Over the past decade, we have seen rapid advances in applying nanotechnology in
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …
Metal drugs and the anticancer immune response
B Englinger, C Pirker, P Heffeter, A Terenzi… - Chemical …, 2018 - ACS Publications
The immune system deploys a multitude of innate and adaptive mechanisms not only to
ward off pathogens but also to prevent malignant transformation (“immune surveillance”) …
ward off pathogens but also to prevent malignant transformation (“immune surveillance”) …
Reprogramming of tumor-associated macrophages with anticancer therapies: radiotherapy versus chemo-and immunotherapies
Tumor-associated macrophages (TAMs) play a central role in tumor progression, metastasis,
and recurrence after treatment. Macrophage plasticity and diversity allow their classification …
and recurrence after treatment. Macrophage plasticity and diversity allow their classification …
Molecular repolarisation of tumour-associated macrophages
FJ Van Dalen, MHME Van Stevendaal, FL Fennemann… - Molecules, 2018 - mdpi.com
The tumour microenvironment (TME) is composed of extracellular matrix and non-mutated
cells supporting tumour growth and development. Tumour-associated macrophages (TAMs) …
cells supporting tumour growth and development. Tumour-associated macrophages (TAMs) …
Exosome-based nanoimmunotherapy targeting TAMs, a promising strategy for glioma
H Luo, H Zhang, J Mao, H Cao, Y Tao, G Zhao… - Cell Death & …, 2023 - nature.com
Exosomes, the cell-derived small extracellular vehicles, play a vital role in intracellular
communication by reciprocally transporting DNA, RNA, bioactive protein, chains of glucose …
communication by reciprocally transporting DNA, RNA, bioactive protein, chains of glucose …
A DNA/DMXAA/Metal–Organic Framework Activator of Innate Immunity for Boosting Anticancer Immunity
X Chen, Q Tang, J Wang, Y Zhou, F Li, Y **e… - Advanced …, 2023 - Wiley Online Library
Immunotherapy has achieved revolutionary success in clinics, but it remains challenging for
treating hepatocellular carcinoma (HCC) characterized by high vascularization. Here, it is …
treating hepatocellular carcinoma (HCC) characterized by high vascularization. Here, it is …
Organelle-specific triggered release of immunostimulatory oligonucleotides from intrinsically coordinated DNA–metal–organic frameworks with soluble exoskeleton
DNA has proven of high utility to modulate the surface functionality of metal–organic
frameworks (MOFs) for various biomedical applications. Nevertheless, current methods for …
frameworks (MOFs) for various biomedical applications. Nevertheless, current methods for …
Gold nanoparticles for preparation of antibodies and vaccines against infectious diseases
LA Dykman - Expert review of vaccines, 2020 - Taylor & Francis
Introduction Vaccination remains very effective in stimulating protective immune responses
against infections. An important task in antibody and vaccine preparation is to choose an …
against infections. An important task in antibody and vaccine preparation is to choose an …
Ultrasound-triggered cascade reaction via MnO2-CpG nanoparticles for boosting pyroptosis-mediated cancer immunotherapy
X Wang, M Shen, Y Sun, Q Tang, L Du, S Yang, H Zou… - Nano Today, 2024 - Elsevier
Nanoparticles is promising for enhancing cancer immunotherapy efficacy via the regulation
of tumor microenvironment (TME), but the efficiency of regulation remains challenging …
of tumor microenvironment (TME), but the efficiency of regulation remains challenging …
Immunostimulatory oligonucleotides-loaded cationic graphene oxide with photothermally enhanced immunogenicity for photothermal/immune cancer therapy
Graphene oxide (GO) has attracted tremendous research interest due to its excellent
electrical, thermal, and mechanical properties. Here, we apply the polyethylene glycol (PEG) …
electrical, thermal, and mechanical properties. Here, we apply the polyethylene glycol (PEG) …