The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

Intranasal oxytocin: myths and delusions

G Leng, M Ludwig - Biological psychiatry, 2016 - Elsevier
Despite widespread reports that intranasal application of oxytocin has a variety of behavioral
effects, very little of the huge amounts applied intranasally appears to reach the …

Intranasal oxytocin treatment for social deficits and biomarkers of response in children with autism

KJ Parker, O Oztan, RA Libove, RD Sumiyoshi… - Proceedings of the …, 2017 - pnas.org
Autism spectrum disorder (ASD) is characterized by core social deficits. Prognosis is poor, in
part, because existing medications target only associated ASD features. Emerging evidence …

[HTML][HTML] Oxytocin in general anxiety and social fear: a translational approach

ID Neumann, DA Slattery - Biological psychiatry, 2016 - Elsevier
The neuropeptide oxytocin (OXT) has been revealed as a profound anxiolytic and antistress
factor of the brain, besides its many prosocial and reproductive effects. Therefore, there is …

The correlation between central and peripheral oxytocin concentrations: a systematic review and meta-analysis

M Valstad, GA Alvares, M Egknud… - Neuroscience & …, 2017 - Elsevier
There is growing interest in the role of the oxytocin system in social cognition and behavior.
Peripheral oxytocin concentrations are regularly used to approximate central concentrations …

Appetite-and weight-regulating neuroendocrine circuitry in hypothalamic obesity

HW Gan, M Cerbone, MT Dattani - Endocrine Reviews, 2024 - academic.oup.com
Since hypothalamic obesity (HyOb) was first described over 120 years ago by Joseph
Babinski and Alfred Fröhlich, advances in molecular genetic laboratory techniques have …

Salivary oxytocin concentrations in response to running, sexual self-stimulation, breastfeeding and the TSST: The Regensburg Oxytocin Challenge (ROC) study

TR de Jong, R Menon, A Bludau, T Grund… - …, 2015 - Elsevier
Intranasal oxytocin (OXT) application is emerging as a potential treatment for socio-
emotional disorders associated with abnormalities in OXT system (re-) activity. The crucial …

Does oxytocin increase trust in humans? A critical review of research

G Nave, C Camerer… - … on Psychological Science, 2015 - journals.sagepub.com
Behavioral neuroscientists have shown that the neuropeptide oxytocin (OT) plays a key role
in social attachment and affiliation in nonhuman mammals. Inspired by this initial research …

Determinants of social cognitive aging: Predicting resilience and risk

JD Henry, SA Grainger… - Annual Review of …, 2023 - annualreviews.org
This review focuses on conceptual and empirical research on determinants of social
cognitive aging. We present an integrated model [the social cognitive resource (SCoRe) …

[HTML][HTML] The effects of oxytocin on appetite regulation, food intake and metabolism in humans

L Kerem, EA Lawson - International Journal of Molecular Sciences, 2021 - mdpi.com
The hypothalamic peptide oxytocin and its receptor are involved in a range of physiological
processes, including parturition, lactation, cell growth, wound healing, and social behavior …