Plant natural products targeting bacterial virulence factors

LN Silva, KR Zimmer, AJ Macedo, DS Trentin - Chemical reviews, 2016 - ACS Publications
Decreased antimicrobial efficiency has become a global public health issue. The paucity of
new antibacterial drugs is evident, and the arsenal against infectious diseases needs to be …

Natural heat shock protein 90 inhibitors in cancer and inflammation

TEMM Costa, NM Raghavendra, C Penido - European Journal of Medicinal …, 2020 - Elsevier
Heat shock protein (HSP) 90 is the most abundant HSPs, which are chaperone molecules
whose major roles are cell protection and maintenance by means of aiding the folding, the …

Profiling Key Aroma Compounds of Senecio glaucus L. and their Antimicrobial and Antioxidant Activities: Multiplex of GC‐MS, NMR and In Silico Studies

MM Elghonemy, AF Essa, AF Osman… - Chemistry & …, 2024 - Wiley Online Library
The essential oils of Senecio plants have been used to treat a wide range of ailments. The
current study aimed to extract the essential oil of Senecio glaucus obtained from Egypt's Nile …

[HTML][HTML] Diterpenes specially produced by fungi: Structures, biological activities, and biosynthesis (2010–2020)

FL Zhang, T Feng - Journal of Fungi, 2022 - mdpi.com
Fungi have traditionally been a very rewarding source of biologically active natural products,
while diterpenoids from fungi, such as the cyathane-type diterpenoids from Cyathus and …

Antimicrobials from medicinal plants: an emergent strategy to control oral biofilms

C Milho, J Silva, R Guimarães, ICFR Ferreira… - Applied Sciences, 2021 - mdpi.com
Oral microbial biofilms, directly related to oral diseases, particularly caries and periodontitis,
exhibit virulence factors that include acidification of the oral microenvironment and the …

[HTML][HTML] Therapeutic potential of bryophytes and derived compounds against cancer

A Dey, A Mukherjee - Journal of acute disease, 2015 - Elsevier
Bryophytes, taxonomically placed between the algae and the pteridophytes, are divided into
three classes such as Liverworts, Hornworts and Mosses. Indigenous use involves this small …

Inhibition of quorum sensing in Pseudomonas aeruginosa by sesquiterpene lactones

S Amaya, JA Pereira, SA Borkosky, JC Valdez… - Phytomedicine, 2012 - Elsevier
Six sesquiterpene lactones (SLs) of the goyazensolide and isogoyazensolide-type isolated
from the Argentine herb Centratherum punctatum were evaluated on their ability to inhibit …

Antimicrobial terpenoids as a potential substitute in overcoming antimicrobial resistance

A Sharma, A Biharee, A Kumar, V Jaitak - Current Drug Targets, 2020 - ingentaconnect.com
There was a golden era where everyone thought that microbes can no longer establish
threat to humans but the time has come where microbes are proposing strong resistance …

Natural sesquiterpenoids

BM Fraga - Natural product reports, 2012 - pubs.rsc.org
Covering: 2011. Previous review: Nat. Prod. Rep. 2011, 28, 1580. This review covers the
isolation, structural determination, synthesis and chemical and microbiological …

Sesqui-and triterpenoids from the liverwort Lepidozia chordulifera inhibitors of bacterial biofilm and elastase activity of human pathogenic bacteria

M Gilabert, K Marcinkevicius, S Andujar, M Schiavone… - Phytomedicine, 2015 - Elsevier
Five dammarane-type triterpenoids, five pentacyclic triterpenoids (three of them carrying a
carboxylic acid group), and two aromadendrane-type sesquiterpenoids were isolated from …