It is well established that muscle contractions during exercise lead to elevated levels of
reactive oxygen species (ROS) in skeletal muscle. These highly reactive molecules have …

Redox reactions control fundamental processes of human biology. Therefore, it is safe to
assume that the responses and adaptations to exercise are, at least in part, mediated by …

The muscular dystrophies comprise more than 30 clinical disorders that are characterized by
progressive skeletal muscle wasting and degeneration. Although the genetic basis for many …

Key points Duchenne muscular dystrophy (DMD) is a fatal muscle wasting disease
associated with increased inflammation, oxidative stress and myofibre necrosis. Cysteine …

Intense contractile activity causes a dramatic decline in the force and velocity generating
capacity of skeletal muscle within a few minutes, a phenomenon that characterizes fatigue …

A main implication of cumulative fatigue is the muscle damage that impairs neuromuscular
function and training adaptations. These negative effects may limit performance when …

To develop a rational framework for answering questions about the role of exercise in
Duchenne muscular dystrophy (DMD), we focused on five pathophysiological mechanisms …

Abstract Duchenne Muscular Dystrophy (DMD) is a fatal skeletal muscle wasting disease
presenting with excessive myofibre necrosis and increased inflammation and oxidative …

Aims: Cancer cachexia is a syndrome which results in severe loss of muscle mass and
marked fatigue. Conditioned media from cachexia-inducing cancer cells triggers metabolic …

While oxidative stress pathways are associated with a wide variety of tissue pathologies, its
applications for evaluating and discerning ecological risks are limited. This study seeks to …