The family Flaviviridae contains three genera: Hepacivirus, Flavivirus, and Pestivirus.
Worldwide, more than 170 million people are chronically infected with Hepatitis C virus and …

Acyclovir, valacyclovir, and famciclovir are used for the treatment of herpes simplex virus
(HSV) and varicella-zoster virus (VZV) infections. Helicase-primase inhibitors (HPIs) inhibit …

Nowadays, it's imperative to develop novel antimicrobial agents active against both drug-
sensitive and drug-resistant bacterial infections with favorable profiles as high efficacy, low …

The vast majority of the world population is infected with at least one member of the human
herpesvirus family. Herpes simplex virus (HSV) infections are the cause of cold sores and …

Two novel series of hydrazinyl thiazolyl coumarin derivatives have been synthesized and
fully characterized by IR, 1H NMR, 13C NMR, elemental analysis and mass spectral data …

When the nucleoside analogue acyclovir was introduced in the early 1980s, it presented a
game-changing treatment modality for herpes simplex virus infections. Since then, work has …

Herpes simplex virus infections are the cause of significant morbidity, and currently used
therapeutics are largely based on modified nucleoside analogs that inhibit viral DNA …

Although there has been considerable progress in the development of antiviral agents in
recent years, there is still a pressing need for new drugs both to improve on the properties of …

In the absence of effective vaccines to control herpesvirus infections, nucleosidic antiviral
drugs have been the mainstay of clinical treatment since their development in the late …

Objectives To evaluate and describe the anti-herpesvirus effect of ASP2151, amenamevir, a
novel non-nucleoside oxadiazolylphenyl-containing herpesvirus helicase–primase complex …