Airway hyperresponsiveness (AHR) is a key clinical feature of asthma. The presence of AHR
in people with asthma provides the substrate for bronchoconstriction in response to …

Leukotrienes are clearly involved in airway inflammation and certain clinical features of
asthma. Evolving evidence indicates that leukotriene B 4 has an important role in the …

The first practice parameter on exercise-induced bronchoconstriction (EIB) was published in
2010. This updated practice parameter was prepared 5 years later. In the ensuing years …

Recently, this international task force reported the general considerations for bronchial
challenge testing and the performance of the methacholine challenge test, a “direct” airway …

The goal of “Pathogenesis, Prevalence, Diagnosis, and Management of Exercise-Induced
Bronchoconstriction: A Practice Parameter” is to empower health care specialty practitioners …

Rationale: Exercise-induced bronchoconstriction (EIB) is a highly prevalent condition with
unclear pathogenesis. Two competing theories of the pathogenesis of EIB differ regarding …

Asthma is a heterogeneous syndrome that has been subdivided into physiologic
phenotypes and molecular endotypes. The most specific phenotypic manifestation of asthma …

Exercise-induced bronchoconstriction (EIB) is often used as a measure of bronchial
hyperresponsiveness and employed in epidemiological studies. Different tests are used …

BACKGROUND: Exercise-induced bronchoconstriction (EIB) is a common cause of
symptoms in a subgroup of asthmatic subjects. The pathobiology that makes this group of …

Transient airway narrowing can occur during or following exercise, a phenomenon called
exercise-induced bronchoconstriction (EIB). The main mechanism of EIB is considered to be …