Elemental imaging gives insight into the fundamental chemical makeup of living organisms.
Every cell on Earth is comprised of a complex and dynamic mixture of the chemical elements …

Mass spectrometry imaging (MSI) is a powerful analytical technique that generates maps of
hundreds of molecules in biological samples with high sensitivity and molecular specificity …

Since its inception in the early 80s, inductively coupled plasma–mass spectrometry has
developed to the method of choice for the analysis of elements in complex biological …

Inductively coupled–plasma mass spectrometry (ICP-MS) has transformed our knowledge
on the role of trace and major elements in biology and has emerged as the most versatile …

Metals have a fundamental role in microbiology, and accurate methods are needed for their
identification and quantification. The inability to assess cellular heterogeneity is considered …

As spectral imaging is gaining special attention in the last years, once it allows transforming
the chemical information from a sample surface into a high-resolution image of elemental …

MMP-11 is a member of the matrix metalloproteinase family (MMPs) which are
overexpressed in cancer cells, stromal cells and the adjacent microenvironment. The MMP …

Mass spectrometry‐based techniques can be applied to investigate collagen with respect to
identification, quantification, supramolecular organization, and various post‐translational …

Levels of zinc, along with its mechanistically related metabolites citrate and aspartate, are
widely reported as reduced in prostate cancer compared to healthy tissue and are therefore …

Protein and peptide detection with inductively coupled plasma mass spectrometry (ICP-MS)
can provide their direct and reliable absolute quantification without the need for specific …