Inborn errors of human B cell development, differentiation, and function
B cells develop from hematopoietic stem cells in the bone marrow. Once generated, they
serve multiple roles in immune regulation and host defense. However, their most important …
serve multiple roles in immune regulation and host defense. However, their most important …
Common variable immunodeficiency: more pathways than roads to Rome
XP Peng, A Caballero-Oteyza… - Annual Review of …, 2023 - annualreviews.org
Fifty years have elapsed since the term common variable immunodeficiency (CVID) was
introduced to accommodate the many and varied antibody deficiencies being identified in …
introduced to accommodate the many and varied antibody deficiencies being identified in …
Hepatocellular cystathionine γ lyase/hydrogen sulfide attenuates nonalcoholic fatty liver disease by activating farnesoid X receptor
Inborn errors of immunity (IEIs) consist of numerous rare, inherited defects of the immune
system that affect about 500,000 people in the United States. As advancements in diagnosis …
system that affect about 500,000 people in the United States. As advancements in diagnosis …
Cellular and molecular mechanisms breaking immune tolerance in inborn errors of immunity
In addition to susceptibility to infections, conventional primary immunodeficiency disorders
(PIDs) and inborn errors of immunity (IEI) can cause immune dysregulation, manifesting as …
(PIDs) and inborn errors of immunity (IEI) can cause immune dysregulation, manifesting as …