Isolation and characterization of extracellular vesicles and future directions in diagnosis and therapy

KP De Sousa, I Rossi, M Abdullahi… - Wiley …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are a unique and heterogeneous class of lipid bilayer
nanoparticles secreted by most cells. EVs are regarded as important mediators of …

Biogenesis of extracellular vesicles in protozoan parasites: The ESCRT complex in the trafficking fast lane?

A Cruz Camacho, D Alfandari, E Kozela… - PLoS …, 2023 - journals.plos.org
Extracellular vesicles (EVs) provide a central mechanism of cell–cell communication. While
EVs are found in most organisms, their pathogenesis-promoting roles in parasites are of …

Trypanosoma cruzi-derived exovesicles contribute to parasite infection, tissue damage, and apoptotic cell death during ex vivo infection of human placental explants

A Fernández-Moya, B Oviedo, A Liempi… - Frontiers in Cellular …, 2024 - frontiersin.org
Trypanosoma cruzi, the causative agent of Chagas disease, can be congenitally transmitted
by crossing the placental barrier. This study investigates the role of T. cruzi-derived …

Stress Induces Release of Extracellular Vesicles by Trypanosoma cruzi Trypomastigotes

CI Vasconcelos… - Journal of …, 2021 - Wiley Online Library
All extracellular forms of Trypanosoma cruzi, the causative agent of Chagas disease,
release extracellular vesicles (EVs) containing major surface molecules of the parasite. EV …

[HTML][HTML] Leishmania Vesicle-Depleted Exoproteome: What, Why, and How?

S Esteves, I Costa, S Luelmo, N Santarém… - Microorganisms, 2022 - mdpi.com
Leishmaniasis, a vector-borne parasitic protozoan disease, is among the most important
neglected tropical diseases. In the absence of vaccines, disease management is …

[HTML][HTML] Molecular recognition of surface trans-sialidases in extracellular vesicles of the parasite trypanosoma cruzi using atomic force microscopy (AFM)

A Prescilla-Ledezma, F Linares… - International Journal of …, 2022 - mdpi.com
Trans-sialidases (TS) are important constitutive macromolecules of the secretome present
on the surface of Trypanosoma cruzi (T. cruzi) that play a central role as a virulence factor in …

Synergistic Insecticidal Effect of Photorhabdus luminescens and Bacillus thuringiensis against Fall Armyworm (Spodoptera frugiperda)

TY Chang, C Hsieh, LH Wu - Agriculture, 2024 - mdpi.com
Combining microbial products with different mechanisms of action can produce synergistic
insecticidal effects and slow down the development of resistance. This study evaluated the …

[HTML][HTML] Leishmania 360°: Guidelines for Exosomal Research

ÁM Gabriel, A Galué-Parra, WLA Pereira… - Microorganisms, 2021 - mdpi.com
Leishmania parasites are a group of kinetoplastid pathogens that cause a variety of clinical
disorders while maintaining cell communication by secreting extracellular vesicles …

Pathogens and extracellular vesicles: New paths and challenges to understanding and treating diseases

MI Ramirez, A Marcilla - Molecular Immunology, 2021 - Elsevier
Extracellular vesicles (EVs) have been described in all eukaryotic and prokaryotic cells as
released membranous structures loaded with biomolecules including nucleic acids …

Overview of extracellular vesicles in pathogens with special focus on human extracellular protozoan parasites

J Alvarado-Ocampo, E Abrahams-Sandí… - Memórias do Instituto …, 2024 - SciELO Brasil
Extracellular vesicles (EVs) are lipid-bilayered membrane-delimited particles secreted by
almost any cell type, involved in different functions according to the cell of origin and its …