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Potential therapeutic options for COVID-19: an update on current evidence
Abstract SARS-CoV-2, a novel coronavirus, is the agent responsible for the COVID-19
pandemic and is a major public health concern nowadays. The rapid and global spread of …
pandemic and is a major public health concern nowadays. The rapid and global spread of …
[HTML][HTML] Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics
With more than 5 million fatalities and close to 300 million reported cases, COVID-19 is the
first documented pandemic due to a coronavirus that continues to be a major health …
first documented pandemic due to a coronavirus that continues to be a major health …
How to use COVID-19 antiviral drugs in patients with chronic kidney disease
Antiviral drugs such as Remdesivir (Veklury), Nirmatrelvir with Ritonavir (Paxlovid),
Azvudine, and Molnupiravir (Lagevrio) can reduce the risk for severe and fatal Coronavirus …
Azvudine, and Molnupiravir (Lagevrio) can reduce the risk for severe and fatal Coronavirus …
An overview of SARS-CoV-2 potential targets, inhibitors, and computational insights to enrich the promising treatment strategies
P Kumawat, LK Agarwal, K Sharma - Current Microbiology, 2024 - Springer
The rapid spread of the SARS-CoV-2 virus has emphasized the urgent need for effective
therapies to combat COVID-19. Investigating the potential targets, inhibitors, and in silico …
therapies to combat COVID-19. Investigating the potential targets, inhibitors, and in silico …
Voltammetric determination of daclatasvir dihydrochloride at bimetallic Ag/Co nanoparticles modified carbon paste electrode
In this work, a sensitive and cost-effective voltammetric method was proposed for the
determination of daclatasvir dihydrochloride (DAC. 2HCl) at a bimetallic Ag/Co …
determination of daclatasvir dihydrochloride (DAC. 2HCl) at a bimetallic Ag/Co …
Effect of sofosbuvir-based treatment on clinical outcomes of patients with COVID-19: a systematic review and meta-analysis of randomised controlled trials
CK Hsu, CY Chen, WC Chen, CC Lai, SH Hung… - International Journal of …, 2022 - Elsevier
This systematic review and meta-analysis examined the efficacy of sofosbuvir-based
antiviral treatment against COVID-19 (coronavirus disease 2019). PubMed, Embase …
antiviral treatment against COVID-19 (coronavirus disease 2019). PubMed, Embase …
Targeting emerging RNA viruses by engineered human superantibody to hepatitis C virus RNA-dependent RNA polymerase
K Glab-Ampai, K Kaewchim, T Thavorasak… - Frontiers in …, 2022 - frontiersin.org
RNA-dependent RNA polymerase (RdRp) is a unique and highly conserved enzyme across
all members of the RNA virus superfamilies. Besides, humans do not have a homolog of this …
all members of the RNA virus superfamilies. Besides, humans do not have a homolog of this …
A pharmacometric approach to evaluate drugs for potential repurposing as COVID-19 therapeutics
T Wattanakul, P Chotsiri, I Scandale… - Expert Review of …, 2022 - Taylor & Francis
Introduction Develo** and evaluating novel compounds for treatment or prophylaxis of
emerging infectious diseases is costly and time-consuming. Repurposing of already …
emerging infectious diseases is costly and time-consuming. Repurposing of already …
Dibenzo-18-crown-6-based carbon paste sensors for the nanomolar potentiometric determination of daclatasvir dihydrochloride: An anti-HCV drug and a potential …
YM Ahmed, SS Badawy, FM Abdel-Haleem - Microchemical Journal, 2022 - Elsevier
Daclatasvir dihydrochloride (DAC) is an anti-hepatitis C virus (HCV) drug that has recently
proven to be a promising candidate for the treatment of SARS-CoV-2. Still, there is a lack of …
proven to be a promising candidate for the treatment of SARS-CoV-2. Still, there is a lack of …
[HTML][HTML] Small-molecule antiviral treatments for COVID-19: A systematic review and network meta-analysis
B Zheng, Q Zhao, W Yang, P Feng, C **n, Y Ying… - International Journal of …, 2024 - Elsevier
Objective This study aimed to explore the efficacy and safety of small-molecule antivirals for
treating coronavirus disease 2019 (COVID-19). Methods Seven databases were searched …
treating coronavirus disease 2019 (COVID-19). Methods Seven databases were searched …