Covering: 2015. Previous review: Nat. Prod. Rep., 2016, 33, 382–431 This review covers the
literature published in 2015 for marine natural products (MNPs), with 1220 citations (792 for …

Microorganisms have gained defense systems during the lengthy process of evolution over
millions of years. Such defense systems can protect them from being attacked by invading …

This review covers the literature published in 2015 for marine natural products (MNPs), with
1220 citations (792 for the period January to December 2015) referring to compounds …

Pore-forming toxins (PFTs) are widely distributed in both Gram-negative and Gram-positive
bacteria. PFTs can act as virulence factors that bacteria utilise in dissemination and host …

Sea anemones produce venoms of exceptional molecular diversity, with at least 17 different
molecular scaffolds reported to date. These venom components have traditionally been …

Actinoporins (APs) from sea anemones are~ 20 kDa pore forming toxins with a β-sandwich
structure flanked by two α-helices. The molecular mechanism of APs pore formation is …

Pore forming proteins (PFPs) share the ability of creating pores that allow the passage of
ions, proteins or other constituents through a wide variety of target membranes, ranging from …

Pore-forming proteins (PFPs) punch holes in their target cell membrane to alter their
permeability. Permeabilization of lipid membranes by PFPs has received special attention to …

FGF2 is exported from cells by an unconventional secretory mechanism. Here, we directly
visualized individual FGF2 membrane translocation events at the plasma membrane using …

Pore-forming toxins (PFTs) form holes in membranes causing one of the most catastrophic
damages to a target cell. Target organisms have evolved a regulated response against PFTs …