The human brain undergoes a prolonged period of cortical development that spans multiple
decades. During childhood and adolescence, cortical development progresses from lower …

The field of human behavioral genetics has come full circle. It began by using twin/family
studies to estimate the relative importance of genetic and environmental influences. As large …

Cardiovascular health interacts with cognitive and mental health in complex ways, yet little is
known about the phenotypic and genetic links of heart-brain systems. We quantified heart …

Our understanding of the genetics of the human cerebral cortex is limited both in terms of the
diversity and the anatomical granularity of brain structural phenotypes. Here we conducted a …

Through dynamic transactional processes between genetic and environmental factors,
childhood and adolescence involve reorganization and optimization of the cerebral cortex …

Subcortical brain structures are involved in developmental, psychiatric and neurological
disorders. Here we performed genome-wide association studies meta-analyses of …

Depression, a widespread and highly heritable mental health condition, profoundly affects
millions of individuals worldwide. Neuroimaging studies have consistently revealed …

Addictions are heritable and unfold dynamically across the lifespan. One prominent
neurobiological theory proposes that substance-induced changes in neural circuitry promote …

The X-chromosome has long been hypothesized to have a disproportionate influence on the
brain based on its enrichment for genes that are expressed in the brain and associated with …

The insula is a heterogeneous cortical region, comprised of three cytoarchitecturally distinct
sub-regions (agranular, dysgranular, and granular), which traverse the anterior-posterior …