Stem cell transplantation holds great promise as a potential treatment for currently incurable
retinal degenerative diseases that cause poor vision and blindness. Recently, safety data …

Age-related macular degeneration (AMD) is the leading cause of blindness among the
elderly in developed countries. AMD is classified as either neovascular (NV-AMD) or non …

Transformation of somatic cells with a set of embryonic transcription factors produces cells
with the pluripotent properties of embryonic stem cells (ESCs). These induced pluripotent …

We previously reported a technique for generating retinal pigment epithelia (RPE) and
putative photoreceptors from embryonic stem (ES) cells. Here we tested whether our …

Purpose.: To evaluate cell survival and tumorigenicity of human embryonic stem cell–
derived retinal pigment epithelium (hESC-RPE) transplantation in immunocompromised …

The retinal pigment epithelium (RPE) maintains retinal function as the metabolic gatekeeper
between photoreceptors (PRs) and the choriocapillaries. The RPE and Bruch's membrane …

Large submacular hemorrhage, an uncommon manifestation of neovascular age-related
macular degeneration, may also occur with idiopathic polypoidal choroidal vasculopathy …

Pluripotent stem cells (PSCs) are a potential replacement tissue source for degenerative
diseases. Age-related macular degeneration (AMD) is a blinding disease triggered by …

The advances in retinal imaging technologies have led to enormous innovation towards
diagnostic in current ophthalmology, enabling the practitioner to detect early retinal changes …

Age-related macular degeneration (AMD) is the leading cause of vision loss in older adults
and ultimately leads to the death of photoreceptor cells in the macular area of the neural …