Genomics and the challenging translation into conservation practice

ABA Shafer, JBW Wolf, PC Alves, L Bergström… - Trends in ecology & …, 2015 - cell.com
The global loss of biodiversity continues at an alarming rate. Genomic approaches have
been suggested as a promising tool for conservation practice as scaling up to genome-wide …

The genetic paradox of invasions revisited: the potential role of inbreeding× environment interactions in invasion success

K Schrieber, S Lachmuth - Biological Reviews, 2017 - Wiley Online Library
Invasive species that successfully establish, persist, and expand within an area of
introduction, in spite of demographic bottlenecks that reduce their genetic diversity …

The crucial role of genome-wide genetic variation in conservation

M Kardos, EE Armstrong, SW Fitzpatrick… - Proceedings of the …, 2021 - pnas.org
The unprecedented rate of extinction calls for efficient use of genetics to help conserve
biodiversity. Several recent genomic and simulation-based studies have argued that the …

Inbreeding depression explains killer whale population dynamics

M Kardos, Y Zhang, KM Parsons, H Kang… - Nature Ecology & …, 2023 - nature.com
Understanding the factors that cause endangered populations to either grow or decline is
crucial for preserving biodiversity. Conservation efforts often address extrinsic threats, such …

Measuring individual inbreeding in the age of genomics: marker-based measures are better than pedigrees

M Kardos, G Luikart, FW Allendorf - Heredity, 2015 - nature.com
Inbreeding (mating between relatives) can dramatically reduce the fitness of offspring by
causing parts of the genome to be identical by descent. Thus, measuring individual …

Genomic consequences of intensive inbreeding in an isolated wolf population

M Kardos, M Åkesson, T Fountain, Ø Flagstad… - Nature ecology & …, 2018 - nature.com
Inbreeding (mating between relatives) is a major concern for conservation as it decreases
individual fitness and can increase the risk of population extinction. We used whole-genome …

inbreedR: an R package for the analysis of inbreeding based on genetic markers

MA Stoffel, M Esser, M Kardos… - Methods in Ecology …, 2016 - Wiley Online Library
Heterozygosity–fitness correlations (HFCs) have been widely used to explore the impact of
inbreeding on individual fitness. Initially, most studies used small panels of microsatellites …

Genetic rescue in a severely inbred wolf population

M Åkesson, O Liberg, H Sand, P Wabakken… - Molecular …, 2016 - Wiley Online Library
Natural populations are becoming increasingly fragmented which is expected to affect their
viability due to inbreeding depression, reduced genetic diversity and increased sensitivity to …

Variability in total project and per sample genoty** costs under varying study designs including with microsatellites or SNPs to answer conservation genetic …

EE Puckett - Conservation Genetics Resources, 2017 - Springer
The field of conservation genetics is in the midst of transitioning from microsatellites to single
nucleotide polymorphisms (SNPs) as part of a broader transition from genetic to genomic …

Assessment of identity disequilibrium and its relation to empirical heterozygosity fitness correlations: a meta‐analysis

JM Miller, DW Coltman - Molecular Ecology, 2014 - Wiley Online Library
Heterozygosity fitness correlations (HFC s) have frequently been used to detect inbreeding
depression, under the assumption that genome‐wide heterozygosity is a good proxy for …