Trypanosoma cruzi is the etiological agent of Chagas disease, usually transmitted by
triatomine vectors. An estimated 20 to 30% of infected individuals develop potentially lethal …

The protozoan Trypanosoma cruzi, its mammalian reservoirs, and vectors have existed in
nature for millions of years. The human infection, named Chagas disease, is a major public …

An international study was performed by 26 experienced PCR laboratories from 14 countries
to assess the performance of duplex quantitative real-time PCR (qPCR) strategies on the …

Background The analytical validation of sensitive, accurate and standardized Real-Time
PCR methods for Trypanosoma cruzi quantification is crucial to provide a reliable laboratory …

Over the last 30 years, concomitant with successful transnational disease control programs
across Latin America, Chagas disease has expanded from a neglected, endemic parasitic …

Orally transmitted Chagas disease has become a matter of concern due to outbreaks
reported in four Latin American countries. Although several mechanisms for orally …

Chagas disease, caused by Trypanosoma cruzi, remains a serious public health problem
worldwide. The parasite was subdivided into six distinct genetic groups, called “discrete …

Chagas disease caused by Trypanosoma cruzi is a complex disease that is endemic and an
important problem in public health in Latin America. The T. cruzi parasite is classified into six …

The intergenic region of spliced-leader (SL-IR) genes from 105 Trypanosoma cruzi I (Tc I)
infected biological samples, culture isolates and stocks from 11 endemic countries, from …

Background Mitochondrial DNA is a valuable taxonomic marker due to its relatively fast rate
of evolution. In Trypanosoma cruzi, the causative agent of Chagas disease, the …