Insights into the computer-aided drug design and discovery based on anthraquinone scaffold for cancer treatment: A systematic review
Background In the search for better anticancer drugs, computer-aided drug design (CADD)
techniques play an indispensable role in facilitating the lengthy and costly drug discovery …
techniques play an indispensable role in facilitating the lengthy and costly drug discovery …
An insight into the therapeutic effects of isoliquiritigenin in breast cancer
Breast cancer ranks as the most widespread malignant condition in women, emerging as a
primary contributor to mortality. The primary challenges in cancer treatments involve …
primary contributor to mortality. The primary challenges in cancer treatments involve …
A Novel Tetramethylpyrazine Chalcone Hybrid-HCTMPPK, as a Potential Anti-Lung Cancer Agent by Downregulating MELK
Y Ma, Q Cui, W Zhu, M Wang, L Zhai, W Hu… - Drug Design …, 2024 - Taylor & Francis
Purpose Lung adenocarcinoma currently ranks the leading causes of cancer-related
mortality worldwide. Many anti-inflammation herbs, like tetramethylpyrazine, have shown …
mortality worldwide. Many anti-inflammation herbs, like tetramethylpyrazine, have shown …
Exploring the Synergistic Effect of Thymol with Oxacillin against Methicillin Resistant Staphylococcus aureus
HK Sharma, A Karna, SK Verma, P Gupta… - Indian Journal of …, 2024 - Springer
The rise of antibiotic resistance in recent years poses a major challenge in the management
of bacterial infections caused by Staphylococcus aureus (S. aureus), especially methicillin …
of bacterial infections caused by Staphylococcus aureus (S. aureus), especially methicillin …
Discovery of potent maternal embryonic leucine zipper kinase (MELK) inhibitors of novel chemotypes using structure-based pharmacophores
Maternal embryonic leucine zipper kinase (MELK) is a serine-threonine kinase. Several
studies have revealed its role as a regulator in the tumorigenesis of various cancers …
studies have revealed its role as a regulator in the tumorigenesis of various cancers …
Computational Insight and Anticancer Effect of Cinnamic Acid-Derivative Amide Compounds
AY Alarcón-López, MA Hernández-Serda… - Journal of the Brazilian …, 2024 - SciELO Brasil
In this research, a meticulous screening process was conducted using four servers: Drug
Target Explorer, Swiss Target Predictor, SEA Predictor, and Target Hunter. The primary …
Target Explorer, Swiss Target Predictor, SEA Predictor, and Target Hunter. The primary …